1207682-00-5Relevant academic research and scientific papers
Facile preparation of alkoxybenzoxazoles via direct SNAr on the benzoxazole ring
Germain, Hervé,Harris, Craig S.,Vautier, Michel,Warin, Nicolas
supporting information; experimental part, p. 554 - 556 (2010/10/02)
The synthesis of alkoxybenzoxazoles is in general quite challenging. During our investigation, we discovered that C-4 and C-7 fluoro precursors undergo SNAr with alkoxides affording moderate to excellent yields of substituted product.
