1207681-92-2

Upstream product

• 98-88-4 benzoyl chloride 
• 65896-11-9 2-bromo-6-fluoroaniline 

Downstream Products

• 1207681-96-6 tert-butyl 4-[(2-phenyl-1,3-benzoxazol-4-yl)oxy]piperidine-1-carboxylate 
• 1207681-98-8 4-(benzylthio)-2-phenyl-1,3-benzoxazole 
• 1207682-00-5 N,N-dimethyl-2-[(2-phenyl-1,3-benzoxazol-4-yl)thio]ethanamine 
• 1207681-94-4 4-[(2,4-dimethoxybenzyl)oxy]-2-phenyl-1,3-benzoxazole 
• 1207681-97-7 methyl [(2-phenyl-1,3-benzoxazol-4-yl)oxy]acetate 
• 1207681-95-5 N,N-dimethyl-2-[(2-phenyl-1,3-benzoxazol-4-yl)thio]ethanamine 
• 30616-79-6 4-methoxy-2-phenyl-1,3-benzoxazole 

Relevant academic research and scientific papers

Iridium-catalyzed intramolecular C–N and C–O/S cross-coupling reactions: Preparation of benzoazole derivatives

The irdium-catalyzed intramolecular arylcarbon-hetero cross-coupling reactions with o-haloarylamides or o-haloarylamidine have been effectively achieved using KOAc and just 1 mol% catalyst. The [Ir(cod)Cl]2 was proved to be more potential for smoothly assembling functional structures benzimidazoles, benzoxazoles and benzothiazoles, which was superior to Cu- and Pd-catalyzed systems. Simultaneously, a concise and efficient synthesis of tafamidis was developed in 5-g scale.