1207685-07-1

Basic information

• Product Name: 2,5-bis(benzyloxymethyl)-1,4-diethoxybenzene
• Synonyms: 2,5-bis(benzyloxymethyl)-1,4-diethoxybenzene
• CAS NO: 1207685-07-1
• Molecular Weight: 406.522
• Mol File: 1207685-07-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,5-bis(benzyloxymethyl)-1,4-diethoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-bis(benzyloxymethyl)-1,4-diethoxybenzene(1207685-07-1)
• EPA Substance Registry System: 2,5-bis(benzyloxymethyl)-1,4-diethoxybenzene(1207685-07-1)

Safety Data

• Hazardous Substances Data: 1207685-07-1(Hazardous Substances Data)

Upstream product

• 56150-29-9 1,4-diethoxy-2,5-bis(chloromethyl)benzene 
• 100-51-6 benzyl alcohol 

Downstream Products

• 1207685-10-6 1,4-bis(ethoxy)pillar[5]arene 
• 2749-70-4 bis(benzyloxy)methane 

Relevant articles and documents

Synthesis and inclusion properties of pillar[n]arenes

A detailed study of the reaction conditions revealed that a quantitative cyclocondensation of 1,4-dialkoxy-2,5-bis(alkoxymethyl)-benzenes to pillar[n]arenes can be achieved by catalysis of p-toluenesulfonic acid in CH2Cl2. Major product of this new reaction is in each case a cyclopentamer (n = 5), but small amounts of the pillar[n]arenes with n = 6, 7 and 10 can be obtained as well. Different alkoxy groups in 1- and 4-position lead to regioisomers. All cyclooligomers exist in pillar structures as pair of enantiomers, which show a racemisation at room temperature, which is fast in terms of the NMR time scale. The racemisation process occurs by rotation of the 1,4-phenylene segments in the macrocyclic rings. Pillar[n]arenes exhibit novel host-guest behavior. Springer Science+Business Media B.V. 2012.