1207737-19-6Relevant articles and documents
Remarkable high-yielding chemical modification of gold nanoparticles using uncatalyzed click-type i ,3-dipolar cycloaddition chemistry and hyperbaric conditions
Ismaili, Hossein,Alizadeh, Abdoihamid,Snell, Kristen E.,Workentin, Mark S.
experimental part, p. 1708 - 1715 (2010/01/29)
Azide-terminated alkyl thiolate monolayer-protected gold nanoparticles (1-C,12MPN) with a core size of 1.8 ± 0.2 nm were prepared. 1-C,12MPN was modified in high yields via an uncatalyzed 1,3-dipolar cycloaddition (clicktype reaction) with a variety of terminal acyl alkynes under hyperbaric conditions at 11 000 atm. The resulting 1,2,3-tria- zole modified MPNs (2-C,12MPN) were characterized using 1H NMR spectroscopy and were verified by comparison of the spectra to those obtained for the products of the model reactions of 1-azidododecane with the same alkynes. TEM analysis showed that the high-pressure conditions did not affect the size of the gold core, suggesting that the only effect is to facilitate the chemical reaction on the particles.