13733-78-3

Basic information

• Product Name: Dodecane, 1-azido-
• Synonyms: 1-dodecaneazide;n-dodecyl azide;Dodecane,1-azido;1-azido-dodecane;1-dodecyl azide;Me(CH2)11N3
• CAS NO: 13733-78-3
• Molecular Formula: C12H25N3
• Molecular Weight: 211.351
• Mol File: 13733-78-3.mol
• Article Data: 41

Chemical Properties

• CAS DataBase Reference: Dodecane, 1-azido-(CAS DataBase Reference)
• NIST Chemistry Reference: Dodecane, 1-azido-(13733-78-3)
• EPA Substance Registry System: Dodecane, 1-azido-(13733-78-3)

Safety Data

• Hazardous Substances Data: 13733-78-3(Hazardous Substances Data)

Upstream product

• 112-52-7 1-chlorododecane 
• 112-41-4 1-dodecene 
• 941-55-9 4-toluenesulfonyl azide 
• 18536-91-9 dodecyltriethoxysilane 
• 112-53-8 1-dodecyl alcohol 
• 10157-76-3 dodecyl 4-methylbenzenesulphonate 
• 4292-19-7 1-Iodododecane 
• 143-15-7 1-dodecylbromide 
• 99-24-1 methyl galloate 
• 106-96-7 propargyl bromide 

Downstream Products

• 929-73-7 dodecylammonium chloride 
• 1009089-52-4 1-(n-dodecyl)-4-(phenyl)-1H-1,2,3-triazole 
• 1310741-06-0 1,2-bis(1-dodecyl-5-iodo-1H-1,2,3-triazol-4-yl)benzene 
• 1310741-03-7 5-bromo-4-(2-(bromoethynyl)phenyl)-1-dodecyl-1H-1,2,3-triazole 
• 1310741-01-5 1,2-bis(5-bromo-1-dodecyl-1H-1,2,3-triazol-4-yl)benzene 
• 1350743-89-3 4,4'-bis-{2-[3,5-bis((1-dodecyl-1H-[1,2,3]triazol-4-yl)methoxy)phenyl]ethyl}-[2,2']bipyridine 
• 16891-99-9 1-nitrododecane 
• 1376606-11-9 1-dodecyl-5-phenethyl-1H-1,2,3-triazole 
• 1376605-89-8 4-((4-chloro-2-methoxyphenoxy)methyl)-1-dodecyl-1H-1,2,3-triazole 
• 1376606-01-7 4-benzyl-1-dodecyl-1H-1,2,3-triazole 
• 1376605-87-6 1-dodecyl-4-(phenoxymethyl)-1H-1,2,3-triazole 
• 1399679-85-6 1-dodecyl-4-[(phenylselanyl)methyl]-1H-1,2,3-triazole 
• 1478053-98-3 C₄₄H₅₉N₆O₂PS₂ 
• 1414891-23-8 1-dodecyl-4-(p-methoxyphenyl)-1,2,3-triazole 

Relevant articles and documents

Hydrogen Bonding-Induced H-Aggregation for Fluorescence Turn-On of the GFP Chromophore: Supramolecular Structural Rigidity

To turn on the fluorescence of the native green fluorescence protein (GFP) chromophore, 4-hydroxybenzylidene-dimethylimidazolinone (HBDI), in an artificial supramolecular system has been a challenging task, because it requires high local environmental rigidity. This work shows that the formation of H-aggregates of an HBDI-containing organogelator results in two orders of magnitude fluorescence enhancement (Φf=2.9 vs. 0.02 %), in which the inter-HBDI OH???OH H-bonds play a crucial role. The aggregation-induced fluorescence enhancement of HBDI has important implications on the origin of the high fluorescence quantum efficiency of HBDI in the GFP β-barrel and on the supramolecular strategy for a full fluorescence recovery of HBDI. These results reveal a new approach to designing rigid chromophore aggregates for high-performance optoelectronic properties.

Mode of action investigation for the antibacterial cationic anthraquinone analogs

Reported previously by our group, we have developed a novel class of antibacterial cationic anthraquinone analogs with superb potency (MIC 1 μg/mL) against Gram positive (G+) pathogens including Methicillin-resistant Staphylococcus aureus (MRSA). However, most of these compounds only manifest modest antibacterial activity against Gram negative (G-) bacteria. Further investigation on the antibacterial mode of action using fluorogenic dyes reveals that these compounds exert two different modes of action that account for the difference in their antibacterial profile. It was found that most of the compounds exert their antibacterial activity by disrupting the redox processes of bacteria. At high concentration, these compounds can also act as membrane disrupting agents. This information can help to design new therapeutics against various bacteria.

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SYNTHESE D'AZOTURES D'ALKYLES A LONGUES CHAINES ET ETUDE DE LEUR AGREGATION EN SOLUTION DANS LE FORMAMIDE

A new method for synthesis of alkyl azides is described.These compounds with long alkylchains, insoluble in water, are surfactants and micellize in formamide.

Zwitterionic and mesoionic liquids: Molecular aggregation in 3-methylsydnone

Ionic liquids are green solvents with interesting properties: displaying low melting points and high boiling points. They offer a new approach applicable in many instances. Nevertheless, the presence of free ions can be a matter in some cases, e.g. for the study of nucleophilic reactions, in electrochemistry, and in each situation where there is a competition between counter ions, as in micellization of ionic surfactants. Neutral compounds having formal unit electrical charges of opposite sign, and the same physical properties than ionic liquids would be a nice alternative to these latter solvents. There are two classes of chemical compounds having these characteristics: zwitterionic liquids (with no uncharged canonical representation) and mesoionic liquids (in which the negative and the positive charges are delocalized). In that last class we have chosen to work with 3-methylsydnone in order to examine, in this aprotic solvent, if it was possible to observe aggregation of surfactants in the same manner as in water. With all kinds of surfactants studied (ionic, zwitterionic and mesoionic) we have been able to demonstrate the formation of direct micelles: hydrogen bonding is thus not mandatory for molecular aggregation. Comparison of the behavior in water and in formamide showed that solvophobic interactions were qualitatively comparable but with a lower intensity.

Synthesis of amphiphilic graphitic silver nanoparticles with inherent internal standards: an efficient strategy for reliable quantitative SERS analysis in common fluids

An efficient strategy for reliable quantitative SERS analysis in common fluids was proposed by amphiphilic functionalization of graphitic silver nanoparticles with inherent internal standards by azides, and has the merits of high accuracy, enhanced dispersity and outstanding stability in fluids.

Step-by-Step Layer-by-Layer Assembly Using 1,2,3-Triazole as a Platform for Controlled Multicharged and Multifunctional Coatings

Reported for the first time is the use of click chemistry to make layer-by-layer multiple post-functionalization treatments. The use of triazole as a platform for the post-functionalization allows the introduction of new clickable structures on the surface. The layer-by-layer strategy by means of click chemistry allows the introduction of both multiple and/or different consecutive modifications on the surface and multicharged species. Herein it consists of the use of molecules functionalized by a 1-azido group and propargyl bromide to deposit functionalized triazolium-type charged oligomers on the substrate. Moreover, different functional groups can be introduced at each step, which amplifies the use of this strategy for many potential applications. Here, to give an example of applications, that strategy is used to introduce alkyl chains and obtain highly hydrophobic materials. Moreover, it is shown that the surface morphology can also change after each treatment.

Antioxidant and Antibacterial Activities of Dodecyl Tannin Derivative Linked with 1,2,3-Triazole

Dodecyl tannin derivative linked with 1,2,3-triazole was prepared by the click reaction of dodecyl azide and alkynylated tannin. The structure of tannin derivative was identified by FT-IR spectrometer and elemental analyzer, and the surface activity, antioxidant activity and antimicrobial activity of tannin derivative were studied. The surface tension of tannin derivative was significantly reduced because of the introduction of long chain alkyl groups, and the lowest surface tension was 38.87 mN/m at 1.0 mg/mL. The tannin derivative had strong ability to scavenge 1,1-diphenyl-2-picrylhydrazyl radical, the scavenging rate could reach 89.08 % at 0.25 mg/mL. The tannin derivative exhibited strong antibacterial activity against E. coli and S. aureus due to the increased fat-solubility of tannin derivative and the introduction of antibacterial triazole groups in molecular structure of tannin derivative, and the bacteriostatic ratios of tannin derivative against E. coli and S. aureus were 92.16 % and 89.21 % at 2.0 mg/mL, respectively. The tannin derivative can be used as good candidates for antibacterial packaging or antioxidant supplements.

ENVIRONMENTALLY-FRIENDLY HYDROAZIDATION OF OLEFINS

The present invention provides processes for the synthesis of organic azides, intermediates for the production thereof, and compositions related thereto.