1207986-35-3Relevant academic research and scientific papers
Synthesis of (S)-ketamine via [1,3]-chirality transfer of a stereocenter created by enantioselective aldol reaction
Yokoyama, Takeshi,Yokoyama, Reiko,Nomura, Satoshi,Matsumoto, Satoshi,Fujiyama, Ryoji,Kiyooka, Syun-Ichi
, p. 1528 - 1532 (2009)
The stereocenter in the intermediate alcohol (86% ee), created by enantioselective oxazaborolidinone-promoted aldol reaction, was transferred to the stereocenter in the cyclohexanone ring, necessary for (S)-ketamine, viaallyl cyanate-to-isocyanate rearran
