1207997-06-5Relevant academic research and scientific papers
Synthesis of zwitterionic salts of pyridinium-meldrum acid and barbiturate through unique four-component reactions
Wang, Qi-Fang,Hui, Li,Hou, Hong,Yan, Chao-Guo
, p. 260 - 265 (2010)
An efficient synthetic procedure for the preparation of the unusual charge-separated pyridinium-Meldrum acid and N,N-dimethylbarbiturate acid zwitterionic salts was developed though a unique one-pot fourcomponent reaction involving pyridine, aromatic aldehyde, Meldrum acid or N,N-dimethylbarbituric acid, and p-nitrobenzyl bromide in acetonitrile. By varying combinations of four components involving nitrogencontaining heterocycles, we conveniently established reactiveα-halomethylene compounds, aldehydes and β-dicarbonyl compounds a library of zwitterionic salts.
