1208-78-2

Usage

Physical appearance

Clear, colorless to pale yellow liquid Describes the compound's appearance, ranging from being transparent with no color to having a light yellow shade.

Odor

Strong, sweet floral odor The scent of the compound, characterized as a powerful and pleasant floral fragrance.

Primary uses

Perfumes, soaps, cosmetics, and personal care products The main applications of the compound, which include its incorporation into various consumer products for fragrance purposes.

Flavoring agent

Food and beverage industry The compound's use as a flavoring agent in the production of food and drink items.

Safety precautions

Potential irritation to eyes, skin, and respiratory system Warning to handle the chemical with care due to possible adverse effects from prolonged or high-level exposure.

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 108-03-2 1-Nitropropane 
• 2393-23-9 4-methoxy-benzylamine 

Downstream Products

• 53917-01-4 1-(4-methoxyphenyl)butan-2-one 
• 85629-16-9 1-(4-methoxy-phenyl)-butan-2-one oxime 
• 145028-34-8 [1-(4-Methoxy-phenyl)-2-oxo-butyl]-phosphonic acid diethyl ester 
• 1301127-24-1 diethyl (S)-3-ethyl-4-(4-methoxyphenyl)-4,5-dihydroisoxazole-5,5-dicarboxylate 2-oxide 

Relevant academic research and scientific papers

Substrate promiscuity of ortho-naphthoquinone catalyst: Catalytic aerobic amine oxidation protocols to deaminative cross-coupling and n-nitrosation

ortho-Naphthoquinone-based organocatalysts have been identified as versatile aerobic oxidation catalysts. Primary amines were readily cross-coupled with primary nitroalkanes via deaminative pathway to give nitroalkene derivatives in good to excellent yields. Secondary and tertiary amines were inert to ortho-naphthoquinone catalysts; however, secondary nitroalkanes were readily converted by ortho-naphthoquinone catalysts to the corresponding nitrite species that in situ oxidized the amines to the corresponding N-nitroso compounds. Without using harsh oxidants in a stoichiometric amount, the present catalytic aerobic oxidation protocol utilizes the substrate promiscuity feature to provide a facile access to amine oxidation products under mild reaction conditions.

Synthesis of Benzo[4,5]imidazo[2,1-b]thiazole by Copper(II)-Catalyzed Thioamination of Nitroalkene with 1H-Benzo[d]imidazole-2-thiol

A Copper(II)-catalyzed thioamination of β-nitroalkene with 1H-benzo[d]imidazole-2-thiol has been developed for the synthesis of benzo[4,5]imidazo[2,1-b]thiazole derivatives. A variety of N-fused benzoimidazothiazole derivatives are obtained in high yields through successive C?N and C?S bond formations. This protocol is also applicable to β-substituted β-nitroalkenes to afford 2,3-disubstituted benzoimidazothiazoles. (Figure presented.).

Straightforward synthesis of nitroolefins by microwave- or ultrasound-assisted Henry reaction

β-Nitroalcohol or nitroethylene derivatives can be obtained from aryl aldehydes and nitromethane under Henry condensation conditions. We present a new modification using microwave irradiation or ultrasound as the energy source. Microwave irradiation allowed a novel one-pot synthesis of nitroolefins from aryl aldehydes using ammonium acetate as a catalyst without solvent. Different reaction conditions, such as base, solvent, and reaction time were studied. Only small amounts of β-hydroxyl nitro compounds were isolated, using microwave irradiation for less than 25 min. In contrast, the use of ultrasound increased the yield of the nitroalcohols.