1208003-53-5Relevant academic research and scientific papers
Gold- and platinum-catalyzed formal Markownikoff's double hydroamination of alkynes: A rapid access to tetrahydroquinazolinones and angularly-fused analogues thereof
Patil, Nitin T.,Kavthe, Rahul D.,Raut, Vivek S.,Shinde, Valmik S.,Sridhar, Balasubramanian
, p. 1277 - 1280 (2010)
(Chemical Equation Presented) A highly efficient gold(I)- and platinum(II)-catalyzed process for formal Markownikoff's double hydroamination of alkynes tethered with hydroxyl group has been developed. The method was shown to be applicable to a broad range of 2-aminobenzamides and alkynols leading to the formation of multiply substituted tetrahydroquinazolinones. Interestingly, when Pt(IV)Cl4 catalyst was employed, cyclic angularly fused compound was obtained. 2010 American Chemical Society.
