1208076-65-6 Usage
General Description
(4-bromo-3-chlorophenyl)methanamine is a chemical compound with the formula C7H7BrClN. It is also known as 3-amino-4-bromo-2-chlorobenzylamine and is a member of the class of anilines, which are organic compounds containing a phenyl group attached to an amino group. (4-bromo-3-chlorophenyl)methanamine has potential applications in the field of organic synthesis and pharmaceuticals. It may be used in the production of various pharmaceutical drugs, as well as in the synthesis of other organic compounds. Additionally, its properties and potential reactivity make it a valuable tool in the study of chemical reactions and mechanisms in organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1208076-65-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,8,0,7 and 6 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1208076-65:
(9*1)+(8*2)+(7*0)+(6*8)+(5*0)+(4*7)+(3*6)+(2*6)+(1*5)=136
136 % 10 = 6
So 1208076-65-6 is a valid CAS Registry Number.
1208076-65-6Relevant articles and documents
Site-Selective Cross-Coupling of Remote Chlorides Enabled by Electrostatically Directed Palladium Catalysis
Golding, William A.,Pearce-Higgins, Robert,Phipps, Robert J.
supporting information, p. 13570 - 13574 (2018/10/20)
Control of site-selectivity in chemical reactions that occur remote from existing functionality remains a major challenge in synthetic chemistry. We describe a strategy that enables three of the most commonly used cross-coupling processes to occur with high site-selectivity on dichloroarenes that bear acidic functional groups. We have achieved this by repurposing an established sulfonylated phosphine ligand to exploit its inherent bifunctionality. Mechanistic studies suggest that the sulfonate group engages in attractive electrostatic interactions with the cation associated with the deprotonated substrate, guiding cross-coupling to the chloride at the arene meta position. This counterintuitive combination of anionic ligand and anionic substrate demonstrates an alternative design principle when considering the application of noncovalent interactions to direct catalysis.
