57418-97-0

Usage

Chemical Properties

off-white crystalline

Upstream product

• 72635-78-0 3-amino-4-bromobenzonitrile 
• 21803-75-8 4-amino-3-chlorobenzonitrile 

Downstream Products

• 914106-28-8 3-chloro-4-[2-(trimethylsilyl)ethynyl]benzonitrile 
• 914106-31-3 3-chloro-4-(3-hydroxy-3-methylbut-1-ynyl)benzonitrile 
• 1308279-93-7 thyl (E)-4-Bromo-3-chlorocinnamate 
• 1261878-70-9 ethyl 3-(4-bromo-3-chlorophenyl)propanoate 
• 1308280-00-3 ethyl 3-[4-(3'-(1-adamantyl)-4'-benzyloxyphenyl)-3-chlorophenyl]propanoate 
• 1308280-06-9 ethyl 3-[4-(3'-(1-adamantyl)-4'-hydroxy)-3-chlorophenyl]propanoate 
• 1308280-12-7 3-[4-(3'-(1-adamantyl)-4'-hydroxy)-3-chlorophenyl]propionic acid 
• 120077-69-2 3-chloro4-bromo-benzaldehyde 
• 1616603-72-5 3-benzyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carbonitrile 
• 1208076-65-6 (4‐bromo‐3‐chlorophenyl)methanamine 
• 945391-06-0 3-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile 

Relevant academic research and scientific papers

Heteroatom-substituted analogues of orphan nuclear receptor small heterodimer partner ligand and apoptosis inducer (E)-4-[3-(1-adamantyl)-4- hydroxyphenyl]-3-chlorocinnamic acid

(E)-4-[3'-(1-Adamantyl)-4'-hydroxyphenyl]-3-chlorocinnamic acid (3-Cl-AHPC) induces the cell cycle arrest and apoptosis of cancer cells. Because its pharmacologic properties-solubility, bioavailability, and toxicity-required improvement for translation, s

Synthesis and in vitro antiprotozoal activities of dicationic 3,5-diphenylisoxazoles

3,5-Bis(4-amidinophenyl)isoxazole (3) - an analogue of 2,5-bis(4- amidinophenyl)furan (furamidine) in which the central furan ring is replaced by isoxazole - and 42 novel analogues were prepared by two general synthetic pathways. The 43 isoxazole derivati

Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles

Novel dicationic 3,5-diphenylisoxazole compounds are described. Synthetic routes to these novel compounds are provided. Several of the compounds displayed in vitro activity versus Trypanosoma brucei brucei and Plasmodium falciparum comparable to that of furamidine. A majority of the novel compounds also were less toxic to VERO cells than furamidine.

PYRAZOLOPYRIMIDINES

The invention relates to the pyrazolopyrimidines of formula (I), wherein R1, R2, R3, R4, R5 and X are defined as in the description. The invention also relates to a method for producing said substances and to their use for controlling undesired microorganisms.