1208129-40-1

Basic information

• Product Name: 2-(phenylthio)-1,3-oxazole
• Synonyms: 2-(phenylthio)-1,3-oxazole
• CAS NO: 1208129-40-1
• Molecular Weight: 177.227
• Mol File: 1208129-40-1.mol

Chemical Properties

• CAS DataBase Reference: 2-(phenylthio)-1,3-oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(phenylthio)-1,3-oxazole(1208129-40-1)
• EPA Substance Registry System: 2-(phenylthio)-1,3-oxazole(1208129-40-1)

Safety Data

• Hazardous Substances Data: 1208129-40-1(Hazardous Substances Data)

Upstream product

• 288-42-6 oxazol 
• 882-33-7 diphenyldisulfane 

Downstream Products

• 1612233-59-6 (S)-6-methyl-1-methylene-7-(2-(phenylthio)oxazol-5-yl)-5,6-dihydro-1H-inden-2(4H)-one 
• 1612233-56-3 (S)-6-methyl-7-(2-(phenylthio)oxazol-5-yl)-5,6-dihydro-1H-inden-2(4H)-one 
• 1612233-54-1 (S)-5-(4-methylocta-1,2-dien-7-yn-3-yl)-2-(phenylthio)oxazole 
• 1612233-52-9 (S)-4-methyl-5-(2-(phenylthio)oxazol-5-yl)hepta-5,6-dienal 
• 1612233-50-7 (S)-4-methyl-5-(2-(phenylthio)oxazol-5-yl)hepta-5,6-dien-1-ol 
• 1612233-48-3 (S)-5-(7-((tert-butyldimethylsilyl)oxy)-4-methylhepta-1,2-dien-3-yl)-2-(phenylthio)oxazole 
• 1612233-47-2 5-iodo-2-(phenylsulfanyl)oxazole 
• 1226781-97-0 5-bromo-2-phenylthio-1,3-oxazole 
• 1208129-41-2 2-(phenylsulfonyl)-1,3-oxazole 

Relevant articles and documents

Total Synthesis of Ajudazol A by a Modular Oxazole Diversification Strategy

The total synthesis of the potent respiratory chain inhibitor ajudazol A was accomplished by a concise strategy in 17 steps (longest linear sequence). The modular approach was based on a direct oxazole functionalization strategy involving a halogen dance

General methodology for the preparation of 2,5-disubstituted-1,3-oxazoles

Chemical equation presented Deprotonation of 2-(phenylsulfonyl)-1,3-oxazole (1) readily provides a useful C-5 carbanion that is reactive with a variety of electrophiles. Aldehydes and ketones are useful substrates, and the formation of 5-iodo- and 5-tri-n-butylstannyl oxazoles affords access to cross-coupling reactions. Subsequent nucleophilic displacement of the 2-phenylsulfonyl group provides a general route for the synthesis of 2,5-disubstituted-1,3-oxazoles.