1208259-34-0Relevant academic research and scientific papers
Copper-catalyzed annulation of amidines for quinazoline synthesis
Lv, Yunhe,Li, Yan,Xiong, Tao,Pu, Weiya,Zhang, Hongwei,Sun, Kai,Liu, Qun,Zhang, Qian
supporting information, p. 6439 - 6441 (2013/08/23)
An efficient Cu-catalyzed synthesis of quinazolines via the C-N bond formation reactions between N-H bonds of amidines and C(sp3)-H bonds adjacent to sulfur or nitrogen atoms in the commonly used solvents, such as DMSO, DMF, DMA, NMP or TMEDA,
Mild and efficient ligand-free copper-catalyzed condensation for the synthesis of quinazolines
Truong, Vouy Linh,Morrow, Michelle
scheme or table, p. 758 - 760 (2010/04/05)
Condensation of o-iodobenzaldehydes 1a_c with amidine hydrochlorides 2a_p under ligand-free copper-catalyzed Ullmann N-arylation conditions afforded the corresponding quinazolines 3a-r in good to excellent yields.
