1208333-53-2Relevant academic research and scientific papers
A novel construction of 2-benzazepine scaffold based on TiCl 4-mediated tandem Mannich reaction - Aromatic electrophilic substitution
Li, Liangxi,Li, Zhiming,Wang, Quanrui
experimental part, p. 2754 - 2761 (2010/04/02)
A novel construction of 2-benzazepine derivatives based on TiCl 4-mediated tandem Mannich reaction of electron-rich benzyl iminium ions with alkenyl ethers and Friedel - Crafts-type alkylation is described. The protocol is amenable to provide the tricyclic furo[3,2-d][2]benzazepine and pyrano[3,2-d][2]benzazepine derivatives, respectively, with 2,3-dihydrofuran or 3,4-dihydro-2H-pyran as the substrates.
