1208348-06-4Relevant academic research and scientific papers
Regioselective intramolecular electrophilic substitution reactions involving π-deficient pyridine substrates: a new entry to pyridoquinazolines and benzo[h][1,6]naphthyridines
Agarwal, Piyush K.,Saifuddin, Mohammad,Kundu, Bijoy
experimental part, p. 862 - 870 (2010/03/25)
Regioselective intramolecular electrophilic substitution reactions have been described in π-deficient pyridine substrates tethered at C-2 to the aryl amine. The presence and nature of ring activating groups at C-6 led to the involvement of either N-1 or C-3 of the pyridine ring in the cyclization thereby leading to the regioselective synthesis of pyridoquinazolines and naphthyridines in excellent yields.
