120853-48-7

Basic information

• Product Name: Benzene, [(1E)-2-[(1S,2R)-2-phenylcyclohexyl]ethenyl]-, rel-
• CAS NO: 120853-48-7
• Molecular Formula: C20H22
• Molecular Weight: 262.395
• Mol File: 120853-48-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzene, [(1E)-2-[(1S,2R)-2-phenylcyclohexyl]ethenyl]-, rel-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [(1E)-2-[(1S,2R)-2-phenylcyclohexyl]ethenyl]-, rel-(120853-48-7)
• EPA Substance Registry System: Benzene, [(1E)-2-[(1S,2R)-2-phenylcyclohexyl]ethenyl]-, rel-(120853-48-7)

Safety Data

• Hazardous Substances Data: 120853-48-7(Hazardous Substances Data)

Upstream product

• 110-52-1 1,4-dibromo-butane 
• 886-65-7 trans,trans-1,4-Diphenyl-1,3-butadiene 

Downstream Products

• 36359-51-0 (+/-)-trans-2-phenylcyclohexanemethanol 

Relevant articles and documents

Facile Formation of Substituted 2-Butene-1,4-diylmagnesium Using Highly Reactive Magnesium: A Simple Approach to Complex Carbocycles and Functionalized Ketones

Substituted 2-butene-1,4-diylmagnesium compounds are readily prepared using highly reactive magnesium.Reactions with organodihalides yield 4-, 5-, and 6-membered carbocycles.In some cases, the initial monoalkylated intermediates can be reacted with other electrophiles.Polyfunctionalized ketones can be prepared in this manner.Depending on the initial 1,3-diene and by the proper choice of electrophiles, either 1,2-, 1,4-, or 2,1-additions may be observed.

Chemistry of Substituted (2-Butene-1,4-diyl)magnesium: A Facile Approach to Complex Carbocycles, Functionalized Ketones and Alcohols, and Silicon-Containing Heterocycles

Highly reactive magnesium reacts with a wide variety of substituted 1,3-dienes to give the corresponding substituted (2-butene-1,4-diyl)magnesium complexes.Reactions of symmetrical (2-butene-1,4-diyl)magnesium with α,ω-alkylene dihalides form three-, four-, five-, and six-membered carbocycles.Significantly, the cyclizations are always stereospecific and completely regioselective.Depending on the initial 1,3-diene and specific electrophiles, uncyclized products can be obtained.Stepwise reactions of (2,3-dimethyl-2-butene-1,4-diyl)magnesium with two different electrophiles afford polyfunctionalized ketones with the generation of a quaternary center.Formal 1,2-additions can be effected in this manner.Substituted five- and six-membered cyclic ketones can also be synthesized in one step by this approach.Treatment of unsymmetrical (2-butene-1,4-diyl)magnesium complexes with triorganosilyl chlorides followed by cyclohexanone results in additions across a terminal double bond with high regioselectivity.Silicon-containing heterocycles or spiro compounds can be readily synthesized by using the bis-Grignard reagents.