886-65-7

Basic information

• Product Name: 1,4-DIPHENYLBUTADIYNE
• Synonyms: α,ω-diphenylbutadiene;TIMTEC-BB SBB008711;DIPHENYLDIACETYLENE;1,4-DIPHENYLBUTADIYNE;1,4-DIPHENYLDIACETYLENE;1,4-diphenylbuta-1,3-diene;trans,trans-1,4-Diphenylbuta-1,3-diene, 98+%;1,4-Diphenyl-1,3-butadiene, scintillation grade, 99+%
• CAS NO: 886-65-7
• Molecular Formula: C16H10
• Molecular Weight: 202.25
• EINECS: 212-952-6
• Mol File: 886-65-7.mol
• Article Data: 315

Chemical Properties

• Melting Point: 86-87 °C(lit.)
• Boiling Point: 350 °C(lit.)
• Flash Point: 190 °C
• Appearance: white to pale yellow crystals or needles
• Density: 1.0426 (estimate)
• Vapor Pressure: 2.97E-05mmHg at 25°C
• Refractive Index: 1.5000 (estimate)
• Merck: 14,3320
• CAS DataBase Reference: 1,4-DIPHENYLBUTADIYNE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-DIPHENYLBUTADIYNE(886-65-7)
• EPA Substance Registry System: 1,4-DIPHENYLBUTADIYNE(886-65-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• F: 10-23
• Hazardous Substances Data: 886-65-7(Hazardous Substances Data)

Usage

Chemical Properties

white to pale yellow crystals or needles

Synthesis Reference(s)

Chemistry Letters, 16, p. 5, 1987Journal of the American Chemical Society, 104, p. 5807, 1982 DOI: 10.1021/ja00385a052Tetrahedron Letters, 33, p. 809, 1992 DOI: 10.1016/S0040-4039(00)77721-5

InChI:InChI=1/C16H14/c1-3-9-15(10-4-1)13-7-8-14-16-11-5-2-6-12-16/h1-14H/b13-7-,14-8-

Upstream product

• 16939-57-4 (E)-buta-1,3-dienylbenzene 
• 100-34-5 benzene diazonium chloride 
• 16844-20-5 1,4-dibromo-1,4-diphenyl-butane 
• 114-70-5 sodium phenylacetate 
• 104-55-2 3-phenyl-propenal 
• 188290-36-0 thiophene 
• 100-42-5 styrene 
• 271-89-6 1-benzofurane 
• 42599-24-6 E-styryl iodide 
• 100-52-7 benzaldehyde 
• 886-66-8 1,4-diphenyl-1,3-butadiyne 
• 103-64-0 bromostyrene 
• 937-58-6 (3E)-4-phenyl-3-buten-1-ol 
• 2243-53-0 trans-styrylacetic acid 

Downstream Products

• 1162-64-7 4,7-diphenyl-2-benzofuran-1,3-dione 
• 22770-13-4 cis-2,5-diphenyl-8-oxabicyclo<4.3.0>non-3-ene-7,9-dione 
• 855288-74-3 phenyl[1, 1’; 4’, 1’’]terphenyl-2’-yl-methanone 
• 56994-68-4 4-nitro-3,5,6-triphenyl-cyclohexene 
• 53991-40-5 diethyl 3,6-diphenyl-1,2,3,6-tetrahydropyridazine-1,2-dicarboxylate 
• 43074-35-7 9-oxo-1,4-bis(phenyl)fluorene 
• 1083-56-3 1,4-diphenylbutane 
• 5808-05-9 (1Z,3E)-1,4-diphenylbuta-1,3-diene 
• 13657-49-3 1,4-diphenylbut-2-ene 
• 6165-44-2 1,4-dicyclohexyl-butane 
• 871874-14-5 2,5-diphenyl-hex-3-enedioic acid 
• 111865-00-0 1,4-diphenyl-but-2-enediyl disodium 
• 54380-72-2 methyl azulene-5-carboxylate 
• 19029-48-2 (+/-)-2,3r,6c-triphenyl-3,6-dihydro-2H-[1,2]oxazine 

Relevant articles and documents

Design of Hemilabile N,N,N-Ligands in Copper-Catalyzed Enantioconvergent Radical Cross-Coupling of Benzyl/Propargyl Halides with Alkenylboronate Esters

The enantioconvergent radical C(sp3)-C(sp2) cross-coupling of alkyl halides with alkenylboronate esters is an appealing tool in the assembly of synthetically valuable enantioenriched alkenes owing to the ready availability, low toxicity, and air/moisture stability of alkenylboronate esters. Here, we report a copper/chiral N,N,N-ligand catalytic system for the enantioconvergent cross-coupling of benzyl/propargyl halides with alkenylboronate esters (>80 examples) with good functional group tolerance. The key to the success is the rational design of hemilabile N,N,N-ligands by mounting steric hindrance at the ortho position of one coordinating quinoline ring. Thus, the newly designed ligand could not only promote the radical cross-coupling process in the tridentate form but also deliver enantiocontrol over highly reactive alkyl radicals in the bidentate form. Facile follow-up transformations highlight its potential utility in the synthesis of various enantioenriched building blocks as well as in the late-stage functionalization for drug discovery.

Ruthenium-catalysed oxidative coupling of vinyl derivatives and application in tandem hydrogenation

The first ruthenium-catalyzed oxidative homo- and cross-coupling of exclusive vinyl derivatives giving highly valued 1,3-diene building blocks is reported. The catalytic system is based on readily available reagents and it mainly delivers the E,E isomer. This methodology also enables the synthesis of adipic acid ester derivatives in a one-pot fashion after in situ ruthenium-catalyzed hydrogenation.

A Solid-Phase Assisted Flow Approach to In Situ Wittig-Type Olefination Coupling

Described herein is the development of a continuous flow, solid-phase triphenylphosphine (PS-PPh3) assisted protocol to facilitate the in situ coupling of reciprocal pairs of halogen and carbonyl functionalised molecular pairs by a Wittig olefination within 15 mins. The protocol entails injecting a single solution (1 : 1 CHCl3 : EtOH) containing the halogenated and carbonyl-based substrates into a continuously flowing stream of CHCl3 : EtOH (1 : 1), passed through a fixed bed of K2CO3 and PS-PPh3. With advancement to the previous PS-PPh3 coupling procedures, the method employs a traditional polystyrene-based immobilisation matrix, the substrate scope of the protocol extended to substituted ketones, secondary alkyl chlorides, and an unprotected maleimide scaffold.