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2,4(1H,3H)-Pyrimidinedione, 1-ethyl-5-fluoro-, also known as 1-Ethyl-5-fluoro-2,4(1H,3H)-Pyrimidinedione, is a pyrimidine derivative with the molecular formula C6H6FN2O2. It is a white to off-white crystalline powder, characterized by a molecular weight of 158.12 g/mol and a melting point of 105-108°C. This chemical compound is widely recognized as a pharmaceutical intermediate, playing a crucial role in the synthesis of antiviral and antitumor drugs. Additionally, it has demonstrated potential in the treatment of autoimmune diseases and inflammatory disorders. Due to its sensitivity, it is essential to handle 2,4(1H,3H)-Pyrimidinedione, 1-ethyl-5-fluoro- with appropriate care to avoid skin, eye, and respiratory irritation.

120889-35-2

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120889-35-2 Usage

Uses

Used in Pharmaceutical Industry:
2,4(1H,3H)-Pyrimidinedione, 1-ethyl-5-fluorois utilized as a pharmaceutical intermediate for the synthesis of antiviral and antitumor drugs. Its unique structure and properties make it a valuable component in the development of medications targeting various viral infections and cancerous conditions.
Used in Autoimmune and Inflammatory Disorder Treatment:
2,4(1H,3H)-Pyrimidinedione, 1-ethyl-5-fluorois also recognized for its potential use in treating autoimmune diseases and inflammatory disorders. Its application in this field is attributed to its capacity to modulate immune responses and reduce inflammation, offering a promising therapeutic option for patients suffering from such conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 120889-35-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,8,8 and 9 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 120889-35:
(8*1)+(7*2)+(6*0)+(5*8)+(4*8)+(3*9)+(2*3)+(1*5)=132
132 % 10 = 2
So 120889-35-2 is a valid CAS Registry Number.

120889-35-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-ethyl-5-fluorouracil

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:120889-35-2 SDS

120889-35-2Downstream Products

120889-35-2Relevant academic research and scientific papers

The photocycloaddition reactions of uridine and related compounds with 2,3-dimethyl-2-butene

Ishikawa,Itoh,Takayanagi,Oshima,Kawahara,Mizuno,Ogura

, p. 1922 - 1930 (2007/10/02)

The photochemical reactions of uracil and 5-fluorouracil derivatives with simple alkenes have been investigated. Photocycloaddition of uracil or 5-fluorouracil derivatives and 2,3-dimethyl-2-butene in acetone gave an enantiomeric mixture of cross cycloadducts (4, 7) in moderate yields. Under similar conditions, diastereomers of 4-substituted 7,7,8,8-tetramethyl-cis-2,4-diazabicyclo[4.2.0]octane-3,5-dione nucleosides (14-17) were formed from uridine or 5-fluorouridine derivatives in good yields. The structures and stereochemistry of these cycloadducts of the nucleoside series were elucidated on the basis of the proton nuclear magnetic resonance spectra and X-ray crystallographic analysis.

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