120891-57-8

Upstream product

• 121222-02-4 1,5-bis(trimethylsilyl)-1,4-pentadien-3-ol 
• 120891-51-2 (2S,3S)-2-[(E)-(S)-1-(1-Ethoxy-ethoxy)-3-trimethylsilanyl-allyl]-3-trimethylsilanyl-oxirane 
• 120891-52-3 [(E)-(S)-3-(1-Ethoxy-ethoxy)-3-(R)-oxiranyl-propenyl]-trimethyl-silane 
• 120891-50-1 (E)-(S)-3-Trimethylsilanyl-1-((2S,3S)-3-trimethylsilanyl-oxiranyl)-prop-2-en-1-ol 
• 120891-53-4 (E)-(3S,4R)-3-(1-Ethoxy-ethoxy)-1-trimethylsilanyl-non-1-en-4-ol 
• 62-23-7 4-nitro-benzoic acid 

Relevant academic research and scientific papers

A HIGHLY PRACTICAL SYNTHESIS OF CHIRAL (E)-1-TRIMETHYLSILYL-1-ALKEN-3,4-DIOLS VIA THE SHARPLESS ASYMMETRIC EPOXIDATION OF 1,5-BIS(TRIMETHYLSILYL)-1,4-PENTADIEN-3-OL. FORMAL TOTAL SYNTHESIS OF LIPOXIN B

The Sharpless asymmetric epoxidation of the alcohol 4 proceeds with an extremely high efficiency to afford the epoxide 5 from which the title chiral alcohol 2 is synthesized in good overall yield.By using the alcohol 2, the Nicolaou's lipoxin B intermedia