1208940-82-2

Upstream product

• 931-53-3 Cyclohexyl isocyanide 
• 108-42-9 3-chloro-aniline 
• 119-67-5 o-carboxybenzaldehyde 

Downstream Products

• 1308652-48-3 2-[N-(3-chloro)phenyl]amino-2-{2-[N-(4-methylbenzyl)carbamoyl]phenyl}acetic acid N-cyclohexyl amide 
• 1208940-89-9 N-cyclohexyl-2-(3-chlorophenyl)-1,3-dihydro-1-oxoisoindol-3-carboxamide 

Relevant academic research and scientific papers

Isolation of Ugi four-component condensation primary adducts: A straightforward route to isocoumarins

(Chemical Equation Presented) Ugi four-component condensation (Ugi-4CC) between 2-formylbenzoic acid, phenacylamine dimethyl acetal, and isocyanides afforded 1H-isochromen-1-ones (isocoumarins). These products, where structure corresponds to the tautomeric enediamine form of the Ugi-4CC primary adducts, were stable enough to allow their isolation and characterization. Stable isocoumarins were also obtained by employing anilines as the amino component In the Ugi four-component condensation.