1209-77-4

Basic information

• Product Name: 3-tert-butyl-1,2,3,4-tetrahydroquinazoline-2,4-dione
• Synonyms: 3-tert-butyl-1,2,3,4-tetrahydroquinazoline-2,4-dione
• CAS NO: 1209-77-4
• Molecular Weight: 218.255
• Mol File: 1209-77-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-tert-butyl-1,2,3,4-tetrahydroquinazoline-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-tert-butyl-1,2,3,4-tetrahydroquinazoline-2,4-dione(1209-77-4)
• EPA Substance Registry System: 3-tert-butyl-1,2,3,4-tetrahydroquinazoline-2,4-dione(1209-77-4)

Safety Data

• Hazardous Substances Data: 1209-77-4(Hazardous Substances Data)

Upstream product

• 5894-65-5 N-t-butylbenzamide 

Downstream Products

• 607-68-1 2,4-dichloroquinazoline 
• 20865-83-2 1‐benzylquinazoline‐2,4(1H,3H)‐dione 
• 1399119-65-3 C₂₁H₂₁FN₂O₄ 
• 1399119-60-8 C₂₃H₂₃FN₄O₅ 
• 1399119-49-3 C₂₆H₂₂FN₅O₄ 
• 1399119-69-7 4-(5-((2,4-dioxo-3,4-dihydroquinazoline-1(2H)-yl)methyl)-2-fluorobenzoyl)-piperazine-1-carboxylic acid tert-butyl ester 
• 1399119-68-6 C₂₁H₂₁FN₄O₄ 
• 1399119-20-0 1-(3-(4-(cyclopropylcarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)quinazoline-2,4(1H,3H)-dione 
• 616890-30-3 1-(4-methoxybenzyl)-1,2,3,4-tetrhydroquinazoline-2,4-dione 
• 616890-56-3 3-tert-butyl-1-(4-methoxybenzyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione 

Relevant articles and documents

Cesium Carboxylate-Promoted Iridium Catalyzed C-H Amidation/Cyclization with 2,2,2-Trichloroethoxycarbonyl Azide

An Ir(III)-catalyzed direct C-H amidation/cyclization of benzamides using 2,2,2-trichloroethoxycarbonyl azide (TrocN3) as the aminocarbonyl source is reported. With the aid of cesium carboxylate, the reactions proceed efficiently and with high regioselectivity, producing various functionalized quinazoline-2,4(1H,3H)-diones, which are important building blocks and key synthetic intermediates for biologically and medicinally important compounds. During the reactions, two new C-N bonds were formed by breaking C-H and N-H bonds sequence.