1209003-99-5Relevant academic research and scientific papers
Preparation of new nitrogen-bridged heterocycles. 68. One-pot synthsis of 4-substituted 5-acylthieno[3,2-d]-thiazole derivatives
Kakehi, Akikazu,Suga, Hiroyuki,Okumura, Yukihisa,Nishi, Takashi
experimental part, p. 175 - 184 (2010/06/14)
The reactions of 5-acyl-3-(1-pyridinio)thiophene-2-thiolates with dimethyl acetylenedicarboxylate in xylene at the reflux temperature afforded the corresponding 2-unsubstituted 5-acylthieno[3,2-d]thiazoles in 25-69% yields together with dimethyl phthalate as another fragmentation product. In a few reactions, the unexpected products, dimethyl 2-[2-acylthieno[2′,3′:2,3]-1,4-thiazino[4,5-a]pyrrol-8-ylidene]succinate derivatives, were also isolated, though their yields were very low.
