1209423-24-4

Basic information

• Product Name: 2,2,2-trichloroethyl (2R,3R,4R,5R,6R)-4,5-dihydroxy-2-(4-iodophenoxy)-6-methyltetrahydro-2H-pyran-3-ylcarbamate
• CAS NO: 1209423-24-4
• Molecular Weight: 540.567
• Mol File: 1209423-24-4.mol

Chemical Properties

• CAS DataBase Reference: 2,2,2-trichloroethyl (2R,3R,4R,5R,6R)-4,5-dihydroxy-2-(4-iodophenoxy)-6-methyltetrahydro-2H-pyran-3-ylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-trichloroethyl (2R,3R,4R,5R,6R)-4,5-dihydroxy-2-(4-iodophenoxy)-6-methyltetrahydro-2H-pyran-3-ylcarbamate(1209423-24-4)
• EPA Substance Registry System: 2,2,2-trichloroethyl (2R,3R,4R,5R,6R)-4,5-dihydroxy-2-(4-iodophenoxy)-6-methyltetrahydro-2H-pyran-3-ylcarbamate(1209423-24-4)

Safety Data

• Hazardous Substances Data: 1209423-24-4(Hazardous Substances Data)

Upstream product

• 17341-93-4 2,2,2-Trichloroethyl chloroformate 

Downstream Products

• 864875-37-6 (2R,3S,4R,5R,6R)-3-hydroxy-6-(4-iodophenoxy)-2-methyl-5-((2,2,2-trichloroethoxy)carbonylamino)tetrahydro-2H-pyran-4-yl benzoate 

Relevant articles and documents

Synthesis of glycocinnasperimicin D

The first total synthesis of amino sugar antibiotic glycocinnasperimicin D (1) has been achieved by a convergent, three-component coupling strategy. The key steps involve the Heck-Mizoroki reaction by using the iodophenyl glycoside 50 and acryl amide 32 to furnish the right core structure of 1, and the construction of the urea glycoside employing the reaction of glycosyl isocyanate 8 with amino sugar 9. Glycosyl isocyanate 8 was prepared by the oxidation of isonitrile 10, which displayed excellent reactivity in the coupling event. Synthetic roadblocks, encountered during this synthetic effort, have led to the development of the α-selective, Lewis acid catalyzed phenyl glycosylation process with 2-amino-hexopyranose and a procedure for acetonide deprotection without affecting the silyl ethers.