120943-79-5

Upstream product

• 100-52-7 benzaldehyde 
• 887588-95-6 3-(tert-butyldimethylsilanyl)-1-phenylprop-2-yn-1-ol 
• 86318-61-8 (tert-butyldimethylsilyl)acetylene 
• 120943-69-3 1-(tert-butyldimethylsilyl)-2-iodo-1-ethanone 
• 120820-58-8 2-bromo-1-tert-butyldimethylsilyl-1-ethanone 
• 120943-70-6 dimethyl <2-(tert-butyldimethylsilyl)-2-oxoethyl>-phosphonate 

Downstream Products

• 144914-79-4 1-(tert-butyldimethylsilyl)-3-phenylpentan-1,4-dione 
• 1266552-00-4 (S,E)-1-(tert-butyldimethylsilyl)-3-phenylprop-2-en-1-ol 
• 1266551-34-1 (R,E)-1-(tert-butyldimethylsilyl)-3-phenylprop-2-en-1-ol 
• 1586870-15-6 N-(1-(tert-butyldimethylsilyl)-3-phenylprop-1-en-1-yl)-p-toluenesulfonamide 
• 1586869-99-9 N-((E)-1-(tert-butyldimethylsilyl)-3-phenylallylidene)-p-toluenesulfonamide 
• 1266551-56-7 (S,E)-3-(tert-butyldimethylsilyl)-1-phenylallyl 4-nitrobenzoate 
• 1266551-53-4 (S,E)-1-(tert-butyldimethylsilyl)-3-phenylallyl 4-nitrobenzoate 

Relevant academic research and scientific papers

Lewis Acid-Assisted Photoinduced Intermolecular Coupling between Acylsilanes and Aldehydes: A Formal Cross Benzoin-Type Condensation

Intermolecular carbon–carbon bond-forming reaction between readily available acylsilanes and aldehydes was achieved under photoirradiation conditions with assistance of a catalytic amount of Lewis acid. Nucleophilic addition of photochemically generated s

Enantio-, Regio- and Chemoselective Copper-Catalyzed 1,2-Hydroborylation of Acylsilanes

Enantioselective synthesis of synthetically significant (α-hydroxyallyl)silanes, (α-hydroxyaryl)silanes, and (α-hydroxyalkyl)silanes is reported. The present copper-catalyzed 1,2-selective hydroborylation of acylsilanes affords the aforementioned products

Stereoselective anti-SN2′ Mitsunobu reaction of α-hydroxy-α-alkenylsilanes

A novel silyl group-directed anti-SN2′ reaction of allylic alcohols under Mitsunobu reaction conditions is described. The Mitsunobu reaction of α-hydroxy-α-alkenylsilanes with a TBS or TIPS group gave the anti-SN2′ product, in which regio- and stereochemical outcomes of the reaction depended on the steric bulkiness of the silyl group.

Application of (α-Phosphonoacyl)silane Reagents to the Synthesis of α,β-Unsaturated Acylsilanes

An efficient and convergent synthetic route to α,β-unsaturated acylsilanes has been developed based on the Horner-Wadsworth-Emmons reaction of (α-phosphonoacyl)silanes.The Arbuzov reaction of the (α-iodoacyl)silane 1c with trimethyl phosphite provides access to the phosphonate 2, which can be alkylated by treatment with potassium tert-butoxide and methyl iodide to afford 3.These (α-phosphonoacyl)silane reagents combine smoothly with a variety of aldehydes to furnish α,β-unsaturated acylsilanes 5-13 in good to excellent yield.