1209455-75-3

Upstream product

• 1209455-68-4 2-(2'-(p-methoxyphenyl)ethynyl)-N-(p-methoxyphenylmethyl)benzamide 
• 1403501-68-7 dimethyl 2-(4-methoxybenzyl)isoindolin-1-one-3-yl-phosphonate 
• 123-11-5 4-methoxy-benzaldehyde 
• 2393-23-9 4-methoxy-benzylamine 
• 119-67-5 o-carboxybenzaldehyde 

Relevant academic research and scientific papers

Practical and high stereoselective synthesis of 3-(arylmethylene) isoindolin-1-ones from 2-formylbenzoic acid

Practical and high stereoselective synthesis of 3-(arylmethylene) isoindolin-1-ones is reported. The synthetic method involves the preparation of dimethyl isoindolin-1-one-3-yl-phosphonates by a 'one-pot' three-component reaction of 2-formylbenzoic acid with 4-methoxybenzylamine or aminoacetaldehyde dimethyl acetal and dimethyl phosphite under solvent and catalyst free-conditions, followed by a Horner reaction with several aryl aldehydes.

Dichotomous control of E/Z-geometry in intramolecular cyclization of o-alkynylbenzamide derivatives catalyzed by organic superbase P4-tBu in the presence/absence of water

E/Z does it! An intramolecular cycli-zation reaction of o-alkynylbenzamides that allows dichotomous control of E/Z-geometry has been developed using an organic superbase, P4-tBu, as a catalyst. The presence/absence of water along with the use of an organi