1209458-53-6Relevant articles and documents
Structure-Activity Relationships of Radioiodinated 6,5,6-Tricyclic Compounds for the Development of Tau Imaging Probes
Watanabe, Hiroyuki,Tatsumi, Haruka,Kaide, Sho,Shimizu, Yoichi,Iikuni, Shimpei,Ono, Masahiro
, p. 120 - 126 (2020)
Tau aggregate, which is the main component of the neurofibrillary tangle, is an attractive imaging target for diagnosing and monitoring the progression of Alzheimer's disease (AD). In this study, we designed and synthesized six radioiodinated 6,5,6-tricyc
HETEROARYLBENZIMIDAZOLE COMPOUNDS
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Page/Page column 577, (2017/07/06)
The present invention covers heteroarylbenzimidazole compounds of general formula (I) in which R1, R2, R3, R4 and R5 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative and/or inflammatory disorders, as a sole agent or in combination with other active ingredients.