1210-32-8

Usage

Uses

Used in Pharmaceutical Research and Development:
4-CHLORO-5-HYDRAZINO-2-PHENYL-2,3-DIHYDROPYRIDAZIN-3-ONE is used as a chemical intermediate for the synthesis of potential drug candidates. Its unique structure, which includes a chloro, hydrazino, and phenyl group, may contribute to its potential therapeutic properties, making it a valuable compound for the development of new medications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 4-CHLORO-5-HYDRAZINO-2-PHENYL-2,3-DIHYDROPYRIDAZIN-3-ONE is used as a building block for designing and optimizing new pharmaceutical agents. Its structural features can be modified to enhance its pharmacological activity, selectivity, and safety profile, which is crucial for the advancement of novel therapeutics.
Used in Drug Discovery:
4-CHLORO-5-HYDRAZINO-2-PHENYL-2,3-DIHYDROPYRIDAZIN-3-ONE is employed in drug discovery processes to identify new lead compounds with potential therapeutic effects. Its chemical properties can be assessed and optimized through various screening and testing methodologies to determine its efficacy and suitability as a drug candidate.
Used in Biological Research:
In biological research, 4-CHLORO-5-HYDRAZINO-2-PHENYL-2,3-DIHYDROPYRIDAZIN-3-ONE may be used to study its interactions with biological targets, such as enzymes, receptors, or cellular pathways. Understanding these interactions can provide insights into its potential therapeutic applications and help in the development of more effective treatments for various diseases.

InChI:InChI=1/C10H9ClN4O/c11-9-8(14-12)6-13-15(10(9)16)7-4-2-1-3-5-7/h1-6,14H,12H2

Upstream product

• 1698-53-9 4,5-dichloro-1-phenylpyridazin-6-one 

Downstream Products

• 59026-57-2 2-phenyl-5-benzylidene-hydrazino-4-chloro-3(2H)-pyridazinone 
• 67322-86-5 4-amino-2-phenylpyridazin-3 (2H)-one 
• 59026-48-1 1-benzyl-3,5-diphenyl-1,5-dihydro-pyrazolo[3,4-d]pyridazin-4-one 
• 59026-47-0 5-phenyl-1-methyl-3-phenyl-1H-pyrazolo<3,4-d>pyridazin-4(5H)-one 
• 59026-53-8 4-Chloro-5-{N-methyl-N'-[1-phenyl-meth-(E)-ylidene]-hydrazino}-2-phenyl-2H-pyridazin-3-one 
• 59026-54-9 5-{N-Benzyl-N'-[1-phenyl-meth-(E)-ylidene]-hydrazino}-4-chloro-2-phenyl-2H-pyridazin-3-one 

Relevant academic research and scientific papers

A novel and practical animation of 4,5-dichloropyridazin-3-ones via reduction with hydrazine hydrate

A novel and simple protocol: the direct amination of 4,5-dichloropyridazinones can be carried out in hydrazine hydrate under mild conditions. 4-Chloro-5-hydrazinopyridazin-3-ones serves as a key intermediate in this reduction.

SYNTHESIS OF PYRAZOLOPYRIDAZINE DERIVATIVES- TWO COMPARABLE APPROACHES, RING CONTRACTION THROUGH EXTRUSION OF SULPHUR AND PHOTOCHEMICAL CYCLISATION

Ring contraction of 7-substituted 2-phenyl-4H-pyridazinothiadiazin-8(7H)-ones (5a-d) to 5-substituted 3-phenyl-1H-pyrazolopyridazin-4(5H)-ones (7a-d), through base-induced extrusion of sulphur, is described.Similar reactions proceed, not only on the 4-acetyl derivatives (4a-d) in basic media, but on 5a and the 4-methyl derivative (6a) thermally.Probable mechanism of these reactions are discussed.A comparable approach to the ring contraction, photochemical cyclisation of 2-substituted 5-(1-alkyl-2-benzylidenehydrazino)-4-chloro-3(2H)-pyridazinones (9a-e) to the corresponding 1-alkylpyrazolo-pyridazinone derivatives (8a-e) is also performed.