67322-86-5Relevant academic research and scientific papers
A novel and practical animation of 4,5-dichloropyridazin-3-ones via reduction with hydrazine hydrate
Cao, Song,Qian, Xuhong,Song, Gonghua,Huang, Xiayu
, p. 54 - 55 (2001)
A novel and simple protocol: the direct amination of 4,5-dichloropyridazinones can be carried out in hydrazine hydrate under mild conditions. 4-Chloro-5-hydrazinopyridazin-3-ones serves as a key intermediate in this reduction.
IMIDAZOPYRIDAZINE COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES
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Page/Page column 103; 104, (2015/06/25)
Compounds having the following formula (I), or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.
An efficient and practical method for the synthesis of 1-(2,6- difluorobenzoyl)-3-(2-alkyl-3-oxopyridazin-4-yl)ureas as potential chitin synthesis inhibitors
Cao, Song,Lu, De-Li,Zhao, Chuan-Meng,Li, Li-Na,Huang, Qing-Chun,Qian, Xu-Hong
, p. 779 - 784 (2007/10/03)
A mild and efficient method for the synthesis of 4-amino-3(2H)- pyridazinones from their corresponding 4,5-dichloropyridazinones under microwave-assisted conditions is described. A series of novel chitin synthesis inhibitors, benzoylphenylureas containing
