121007-19-0Relevant academic research and scientific papers
Biosynthesis of Biscognienyne B Involving a Cytochrome P450-Dependent Alkynylation
Abe, Ikuro,Awakawa, Takayoshi,Chen, Guo-Dong,Gao, Hao,Gao, Yao-Hui,Hu, Dan,Liu, Ling,Lv, Jian-Ming,Yao, Xin-Sheng,Zhao, Huan
, p. 13531 - 13536 (2020/06/02)
The alkyne is a biologically significant moiety found in many natural products and a versatile functional group widely used in modern chemistry. Recent studies have revealed the biosynthesis of acetylenic bonds in fatty acids and amino acids. However, the
The Synthesis of Natural Acetylenic Compounds from Eutypa lata (Pers:F.) TUL.
Defranq, Eric,Zesiger, Thierry,Tabacchi, Raffaele
, p. 425 - 430 (2007/10/02)
The synthesis of a series of novel acetylenic compounds 1-7, isolated recently from the fungus Eutypa lata, is described.The crucial step is the coupling reaction between protected aryl halogenide and the acetylenic chain as a cuprous acetylide (Scheme I).A more efficient method using bis(triphenylphosphine)palladium dichloride () as catalyst was also carried out with success.
