121019-73-6

Basic information

• Product Name: 2-Ethyl-4-benzamido-5-phenyloxazole
• Synonyms: 2-Ethyl-4-benzamido-5-phenyloxazole
• CAS NO: 121019-73-6
• Molecular Weight: 292.337
• Mol File: 121019-73-6.mol

Chemical Properties

• CAS DataBase Reference: 2-Ethyl-4-benzamido-5-phenyloxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Ethyl-4-benzamido-5-phenyloxazole(121019-73-6)
• EPA Substance Registry System: 2-Ethyl-4-benzamido-5-phenyloxazole(121019-73-6)

Safety Data

• Hazardous Substances Data: 121019-73-6(Hazardous Substances Data)

Upstream product

• 613-90-1 benzoyl cyanide 
• 126193-96-2 N-benzoyl-1,2,2-trimethoxy-2-phenylethyl amine 
• 107-12-0 propiononitrile 
• 98-88-4 benzoyl chloride 
• 121019-63-4 4-amino-2-ethyl-5-phenyloxazole 

Relevant articles and documents

Nitrile Additions to C,N-Diacylimines. Formation of 4-Amidooxazoles

Nitriles are shown to react with C,N-diacylimines 2, generated in situ from 1 or 4 in the presence of Lewis acids, to produce 4-amidooxazoles 5 and 6 in good to excellent yield.Diamides are sometimes also produced.The reaction was followed by NMR spectros

A New Synthesis of 4-Aminooxazoles from α-Oxonitriles

A general synthesis is described for the preparation of 4-amino-2,5-disubstituted oxazoles 2.The interaction of α-oxonitriles 1 with equimolecular amounts of aromatic or aliphatic aldehydes, and excess of anhydrous ammonium acetate in glacial acetic acid at 110-120 deg C for 3-6 hours gives 2 in 40-65percent yields.A plausible reaction mechanism for the formation of 2 is also suggested.