1210344-13-0

Upstream product

• 106-41-2 4-bromo-phenol 
• 1221506-21-3 (5-bromo-2-fluorophenyl)(4-ethoxyphenyl)methanol 
• 588-96-5 4-bromoethoxybenzene 
• 1181681-00-4 4-bromo-1-fluoro-2-(4-methoxybenzyl)benzene 

Downstream Products

• 1210344-18-5 3-[4-(5-bromo-2-fluorobenzyl)phenoxy]tetrahydrofuran 
• 1210344-19-6 3-[4-(5-bromo-2-fluorobenzyl)phenoxy]oxetane 
• 1360569-09-0 4-bromo-1-fluoro-2-(4-((1-(trifluoromethyl)cyclopropyl)methoxy)benzyl)benzene 
• 1360569-12-5 4-bromo-2-(4-((4,4-difluoro-1-methylcyclohexyl)methoxy)benzyl)-1-fluorobenzene 
• 1360569-14-7 (3R,4R,5S,6R)-2-(3-(4-((4,4-difluoro-1-methylcyclohexyl)methoxy)benzyl)-4-fluorophenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 
• 1360569-13-6 (3R,4S,5S,6R)-2-(3-(4-((4,4-difluoro-1-methylcyclohexyl)methoxy)benzyl)-4-fluorophenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol 
• 1360569-11-4 (3R,4R,5S,6R)-2-(4-fluoro-3-(4-((1-(trifluoromethyl)cyclopropyl)methoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 
• 1360569-10-3 (3R,4S,5S,6R)-2-(4-fluoro-3-(4-((1-( trifluoromethyl)cyclopropyl)methoxy)benzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol 
• 1360569-08-9 (3R,4R,5S,6R)-2-(4-fluoro-3-(4-((1-(trifluoromethyl)cyclobutyl)methoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 
• 1360569-07-8 (3R,4S,5S,6R)-2-(4-fluoro-3-(4-((1-(trifluoromethyl)cyclobutyl)methoxy)benzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol 
• 1360569-46-5 (2S,3R,4R,5S,6R)-2-(4-fluoro-3-(4-((1-(trifluoromethyl)cyclopropyl)methoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 
• 1360569-48-7 (2S,3R₄R₅S,6R)-2-(3-(4-((4,4-difluoro-1-methylcyclohexyl)methoxy)benzyl)-4-fluorophenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 
• 1360569-47-6 (2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(3-(4-((4,4-difluoro-1-methylcyclohexyl)methoxy)benzyl)-4-fluorophenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate 
• 1360569-45-4 (2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-fluoro-3-(4-((1-(trifluoromethyl)cyclopropyl)methoxy)benzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate 

Relevant academic research and scientific papers

CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS

The invention relates to the cycloalkyl methoxybenzyl phenyl pyran derivatives as Sodium dependent glucose co transporter (SGLT) inhibitors, particularly SGLT2 and method of treating diseases, conditions and/or disorders inhibited by SGLT2 with them, and processes for preparing them.

DIOXA-BICYCLO[3.2.1.]OCTANE-2,3,4-TRIOL DERIVATIVES

Compounds of Formula (I) are described herein and the uses thereof for the treatment of diseases, conditions and/or disorders mediated by sodium-glucose transporter inhibitors (in particular, SGLT2 inhibitors).The compounds disclosed herein are useful for the prevention and treatment of obesity and its associated co-morbidities, inn particular type Il (type 2) diabetes.