1210761-18-4

Basic information

• Product Name: ethyl 3-(4-(benzyloxy)phenyl)isoxazole-5-carboxylate
• Synonyms: ethyl 3-(4-(benzyloxy)phenyl)isoxazole-5-carboxylate
• CAS NO: 1210761-18-4
• Molecular Weight: 323.348
• Mol File: 1210761-18-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl 3-(4-(benzyloxy)phenyl)isoxazole-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-(4-(benzyloxy)phenyl)isoxazole-5-carboxylate(1210761-18-4)
• EPA Substance Registry System: ethyl 3-(4-(benzyloxy)phenyl)isoxazole-5-carboxylate(1210761-18-4)

Safety Data

• Hazardous Substances Data: 1210761-18-4(Hazardous Substances Data)

Upstream product

• 698348-95-7 C₁₄H₁₁NO₂ 
• 623-47-2 propynoic acid ethyl ester 
• 76193-67-4 4-benzyloxybenzaldehyde oxime 
• 1210761-17-3 (E)-4-(benzyloxy)-N-hydroxybenzimidoyl chloride 
• 4397-53-9 p-benzyloxybenzaldehyde 
• 188038-42-8 4-benzyloxy-N-hydroxy-benzenecarboximidoyl chloride 
• 123-08-0 4-hydroxy-benzaldehyde 

Downstream Products

• 901929-01-9 3-(4-(benzyloxy)phenyl)isoxazole-5-carboxylic acid 

Relevant articles and documents

A facile one-pot synthesis of 3,5-disubstituted isoxazole derivatives using hydroxy (tosyloxy) iodobenzene

Hydroxy (tosyloxy) iodobenzene (HTIB), a hypervalent iodine reagent, has been extensively used for oxidative transformations. We have developed a one-pot synthesis wherein aldoximes when reacted with alkynes in the presence of HTIB result in the direct formation of isoxazoles. This simple and straightforward reaction allows for ease of purification while leading to the formation of high purity 3,5-disubstituted isoxazoles in moderate yields.

OXAZOLE, OXADIAZOLE AND THIAZOLE DERIVATIVES AS DIACYLGLYCEROL ACYLTRANFERASE INHIBITORS

The present invention relates to isoxazole, thiazole and oxidiazole derivatives, processes for their preparation, pharmaceutical compositions containing them and their use as medicaments, in particular to the use of these compounds in the prevention and treatment of diseases or disorders mediated by diacylglycerol acyltransferase (DGAT), particularly DGAT1.