1210801-46-9

Upstream product

• 90312-02-0 N-(2-hydroxymethylphenyl)-4-methylbenzenesulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 5344-90-1 2-Aminobenzyl alcohol 

Downstream Products

• 1210801-48-1 dimethyl 2-(2-((4-methylphenyl)sulfonamido)benzyl)-malonate 
• 1435943-94-4 N-(2-(3-(4-methoxyphenyl)-3-oxopropyl)phenyl)-4-methylbenzenesulfonamide 
• 1435943-95-5 N-(2-(3-(4-fluorophenyl)-3-oxopropyl)phenyl)-4-methylbenzenesulfonamide 
• 1435943-96-6 N-(2-(3-(furan-2-yl)-3-oxopropyl)phenyl)-4-methylbenzenesulfonamide 
• 1435943-99-9 N-(2-(3-(naphthalen-2-yl)-3-oxopropyl)phenyl)-4-methylbenzenesulfonamide 
• 1435944-00-5 N-(2-(3-oxobutyl)phenyl)-4-methylbenzenesulfonamide 
• 1435944-01-6 N-(2-(3-oxopentyl)phenyl)-4-methylbenzenesulfonamide 
• 1022-86-2 2-benzoylindole 
• 1435944-02-7 N-(2-(4-methyl-3-oxopentyl)phenyl)-4-methylbenzenesulfonamide 
• 1435944-03-8 N-(2-(4,4-dimethyl-3-oxopentyl)phenyl)-4-methylbenzenesulfonamide 
• 104749-68-0 (1H-indol-2-yl)(4-methoxyphenyl)methanone 
• 1435943-93-3 2'-tosylamino-1,3-diphenylpropan-1-one 

Relevant academic research and scientific papers

Production of optically active aromatic compounds having nitrogen atoms in a ring structure comprising

PROBLEM TO BE SOLVED: To provide a production method for obtaining an optically active aromatic compound having a cyclic structure including a nitrogen atom, in which a modified group can be removed while keeping a high yield and optical purity, with a high yield in a high enantioselective manner.SOLUTION: An aromatic compound described below is used as a substrate: in the aromatic compound, an amino group expressed by -NHR11 (where R11 is an arene sulfonyl group) is bonded to one of two carbon atoms constituting a benzene ring and adjoining to each other, and -R13-CHR15-C(=O)-Z (where R13 represents a methylene or an ethylene which may have a substituent, R15 represents a hydrogen atom, an alkyl group which may have a substituent, or a cycloalkyl group which may have a substituent, and Z represents a heteroaryl group which may have a substituent) is bonded to the other carbon atom. The substrate is made to react in a system to which N-spiro C2 axis asymmetric quaternary ammonium iodide and an oxidizing agent are supplied so as to obtain an aromatic compound having a cyclic structure including a nitrogen atom derived from the above amino group.

Iodine-mediated intramolecular amination of ketones: The synthesis of 2-acylindoles and 2-acylindolines by tuning N-protecting groups

A general method for constructing both 2-acylindoles and 2-acylindolines via I2-mediated intramolecular C-N bond formation is presented, and the selective formation of either 2-acylindoles or 2-acylindolines just depends on the nitrogen protecting groups used in the same substrate skeletons. The Royal Society of Chemistry.

Diphosphine-catalyzed mixed double-michael reaction: A unified synthesis of lndolines, Dihydropyrrolopyridines, Benzimidazolines, Tetrahydroquinolines, Tetrahydroisoquinolines, Dihydrobenzo-1,4-oxazines, and Dihydrobenzo-3,1- oxazines

(Figure Presented) Seven different types of benzannulated N-heterocycles-indolines, dihydropyrrolopyridlnes, benzimidazolines, dihydrobenzo-3,1-oxazines, benzomorpholines, tetrahydroquinolines, and tetrahydroisoquinolines-can be obtained from simple dinuc