1210881-27-8

Basic information

• Product Name: 2-phenethylquinoxaline
• Synonyms: 2-phenethylquinoxaline
• CAS NO: 1210881-27-8
• Molecular Weight: 234.301
• Mol File: 1210881-27-8.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 2-phenethylquinoxaline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenethylquinoxaline(1210881-27-8)
• EPA Substance Registry System: 2-phenethylquinoxaline(1210881-27-8)

Safety Data

• Hazardous Substances Data: 1210881-27-8(Hazardous Substances Data)

Upstream product

• 1448-87-9 2-chloroquinoxaline 
• 7251-61-8 2-methylquinoxaline 
• 100-51-6 benzyl alcohol 
• 95-54-5 1,2-diamino-benzene 
• 6640-55-7 2-methyl-1,2,3,4-tetrahydroquinoxaline 
• 100-52-7 benzaldehyde 
• 115419-46-0 tris-β-phenylethylbismuth 
• 36856-91-4 2-bromo-quinoxaline 
• 91838-74-3 2-ethenylquinoxaline 
• 71-43-2 benzene 
• 645-45-4 hydrocinnamic acid chloride 
• 10290-42-3 1-diazo-4-phenyl-2-butanone 

Downstream Products

• 112193-05-2 2-<(E)-2-Phenylethenyl>chinoxalin 
• 1210881-37-0 (S)-2-phenethyl-1,2,3,4-tetrahydroquinoxaline 
• 1350827-73-4 (R)-2-phenethyl-1,2,3,4-tetrahydroquinoxaline 

Relevant articles and documents

Asymmetric hydrogenation of quinoxalines catalyzed by iridium/PipPhos

A catalyst made in situ from the (cyclooctadiene)iridium chloride dimer, [Ir(COD)Cl]2, and the monodentate phosphoramidite ligand (S)-PipPhos was used in the enantioselective hydrogenation of 2- and 2,6-substituted quinoxalines. In the presence

Manganese catalyzed C-alkylation of methylN-heteroarenes with primary alcohols

C-Alkylations of nine different classes of methyl-substitutedN-heteroarenes, including quinolines, quinoxalines, benzimidazoles, benzoxazoles, pyrazines, pyrimidines, pyridazines, pyridines, and triazines are disclosed. A bench stable earth-abundant Mn(i)-complex catalyzed the chemoselective hydrogen-transfer reaction utilizing a diverse range of primary alcohols as the non-fossil fuel-derived carbon source. The diversifiedN-heteroarenes (41 examples) were isolated in high yields and selectivities. Water is produced as the sole byproduct, making the protocol environmentally benign.

Iridium-Catalyzed C-Alkylation of Methyl Group on N-Heteroaromatic Compounds using Alcohols

In this study, we developed a catalytic system for the C-alkylation of a methyl group on N-heteroaromatic compounds, including pyridine, pyrimidine, pyrazine, quinoline, quinoxaline, and isoquinoline, using alcohols based on a hydrogen-borrowing process with [Cp*IrCl2]2 (Cp*: η5-pentamethylcyclopentadienyl) combined with potassium t-butoxide and 18-crown-6-ether as the catalyst precursor.

Iron-catalysed alkylation of 2-methyl and 4-methyl azaarenes with alcoholsviaC-H bond activation

The first Fe-catalysed alkylation of 2-methyl and 4-methyl-azaarenes with a series of alkyl and hetero-aryl alcohols is reported (>39 examples and up to 95% yield). Multi-functionalisation of pyrazines and synthesis of anti-malarial drug (±) Angustureine significantly broaden the scope of this methodology. Preliminary mechanistic investigation, deuterium labeling and kinetic experiments including trapping of the enamine intermediate1a'are of special importance.