121104-86-7

Basic information

• Product Name: [1S-(1α,6β,7α,8β,8aβ)]-octahydro-1,6,7,8-indolizinetetrol 6,7-bis(4-fluorobenzoate)
• CAS NO: 121104-86-7
• Molecular Weight: 433.409
• Mol File: 121104-86-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [1S-(1α,6β,7α,8β,8aβ)]-octahydro-1,6,7,8-indolizinetetrol 6,7-bis(4-fluorobenzoate)(CAS DataBase Reference)
• NIST Chemistry Reference: [1S-(1α,6β,7α,8β,8aβ)]-octahydro-1,6,7,8-indolizinetetrol 6,7-bis(4-fluorobenzoate)(121104-86-7)
• EPA Substance Registry System: [1S-(1α,6β,7α,8β,8aβ)]-octahydro-1,6,7,8-indolizinetetrol 6,7-bis(4-fluorobenzoate)(121104-86-7)

Safety Data

• Hazardous Substances Data: 121104-86-7(Hazardous Substances Data)

Upstream product

• 79831-76-8 (1S,6S,7R,8R,8aR)-2,6,7,8-tetrahydroxy-indolizidine 
• 403-43-0 4-fluorobenzoyl chloride 

Relevant articles and documents

Esters of castanospermine in the treatment of cerebral malaria

Red blood cells which are infected with the parasite P. falciparum cause the cells to become sticky and less deformable. This results in a build-up of cells on the vascular wall and creates occlusions to blood flow which are thought to cause the cerebral, renal and liver complications of P. falciparum infections. Certain esters of castanospermine prevent or reduce the adhesion of falciparum infected blood cells to the vascular endothelial wall and are a useful adjunct in the treatment of malaria.