121125-49-3

Upstream product

• 122048-10-6 <(3-pyridinylcarbonyl)oxy>methyl <2S-(2α,5α,6β)>-3,3-dimethyl-7-oxo-6-<(phenylacetyl)amino>-4-thia-1-azabicyclo<3.2.0>heptane-2-carboxylate 
• 34573-47-2 chloromethyl <2S-(2α,5α,6β)>-3,3-dimethyl-7-oxo-6-<(phenylacetyl)amino>-4-thia-1-azabicyclo<3.2.0>heptane-2-carboxylate 
• 16518-17-5 potassium nicotinate 
• 121125-45-9 <2S-(2α,5α,6β)>-3-<<<<<3,3-dimethyl-7-oxo-6-<(phenylacetyl)amino>-4-thia-1-azabicyclo<3.2.0>hept-2-yl>carbonyl>oxy>methoxy>carbonyl>-1-methylpyridinium iodide 

Downstream Products

• 121125-45-9 <2S-(2α,5α,6β)>-3-<<<<<3,3-dimethyl-7-oxo-6-<(phenylacetyl)amino>-4-thia-1-azabicyclo<3.2.0>hept-2-yl>carbonyl>oxy>methoxy>carbonyl>-1-methylpyridinium iodide 

Relevant academic research and scientific papers

Pharmaceutical formulations for parenteral use

Aqueous parenteral solutions of drugs which are insoluble or only sparingly soluble in water and/or which are unstable in water, combined with cyclodextrin selected from the group consisting of hydroxypropyl, hydroxyethyl, glucosyl, maltosyl and maltotriosyl derivatives of β- and γ-cyclodextrin, provide a means for alleviating problems associated with drug precipitation at the injection site and/or in the lungs or other organs following parenteral administration.

Brain-Specific Chemical Delivery Systems for β-Lactam Antibiotics. Synthesis and Properties of Some Dihydropyridine and Dihydroisoquinoline Derivatives of Benzylpenicillin

Six chemical delivery systems (CDS) were synthesized for benzylpenicillin in order to improve its transport across the blood-brain barrier.The CDS's were based on a dihydropyridine quaternary pyridinium ion redox system, analogous to the naturally occ