1211284-93-3

Upstream product

• 106-39-8 bromochlorobenzene 
• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 78317-78-9 2-(4-chlorophenyl)-1,2,3,4-tetrahydroisoquinoline 
• 75-52-5 nitromethane 
• 637-87-6 1-Chloro-4-iodobenzene 

Downstream Products

• 6772-55-0 2-(4-chlorophenyl)-3,4-dihydroisoquinolin-1(2H)-one 

Relevant academic research and scientific papers

Importance of Singlet Oxygen in Photocatalytic Reactions of 2-Aryl-1,2,3,4-tetrahydroisoquinolines Using Chalcogenorosamine Photocatalysts

Aerobic oxidation of 2-aryl-1,2,3,4-tetrahydroisoquinolines was achieved photocatalytically using chalcogenorosamine photocatalysts and LED irradiation. The photocatalytic aza-Henry reaction between these substrates and nitromethane was more efficient wit

Direct Near Infrared Light–Activatable Phthalocyanine Catalysts

The high penetration of near-infrared (NIR) light makes it effective for use in selective reactions under light-shielded conditions, such as in sealed reactors and deep tissues. Herein, we report the development of phthalocyanine catalysts directly activa

Tetrathienoanthracene-functionalized conjugated microporous polymers as an efficient, metal-free visible-light solid organocatalyst for heterogeneous photocatalysis

Owing to their advantages of superior inherent porosity, high chemical stability, light weight, and molecularly tunable optoelectronic properties, conjugated microporous polymers (CMPs) have been receiving increasing attention and research interest as pro

Cross-dehydrogenative Coupling of N-Aryl Tetrahydroisoquinolines Catalyzed by an Anthraquinone-containing Polymeric Photosensitizer

This work reports the photocatalytic application of an anthraquinone-containing polymeric photosensitizer (AQ-PHEMA) in the visible light-induced cross-dehydrogenative-coupling of N-aryl tetrahydroisoquinolines with several nucleophiles, including nitromethane, 1-methyl-2-alkyl ketone and dialkyl (aryl) phosphine oxide. The results revealed that the reaction could be catalyzed by AQ-PHEMA efficiently to afford a series of 1-substituted-2-aryl-1,2,3,4-tetrahydroisoquinolines in good to excellent yields with nice substrate tolerance under aerobic conditions at room temperature. The practical application potential was also showcased by a gram-scale synthesis. More importantly, the utilization of AQ-PHEMA as a heterogeneous photosensitizer also showed nice recyclability and reusability of the catalyst, whereas AQ-PHEMA can be easily separated and reused for at least 8 times without significant loss of photocatalytic activity.

Flowers of the plant genusHypericumas versatile photoredox catalysts

Photoredox catalysis is a powerful and modern strategy for the synthesis of complex organic molecules. So far, this field has relied on the use of a limited range of metal-based chromophores or artificial organic dyes. Here, we show that the ubiquitous plant genusHypericumcan be used as an efficient photoredox catalyst. The dried flowers efficiently catalyze two typical photoredox reactions, a photoreduction and a photooxidation reaction, with a versatile substrate scope. Constitution analysis of the worldwide available plant genus indicated that naphthodianthrones, namely the compounds of the hypericin family, are crucial for the photocatalytic activity of the dried plant material.In situUV-vis spectroelectrochemical methods provide insights into the mechanism of the photoreduction reaction where the radical dianion of hypericin (Hyp˙2?) is the catalytically active species. Our strategy provides a sustainable, efficient and an easy to handle alternative for a variety of visible light induced photocatalytic reactions.

A LADH-like Zn-MOF as an efficient bifunctional catalyst for cyanosilylation of aldehydes and photocatalytic oxidative carbon–carbon coupling reaction

The rational design of component and coordination configuration of active center is critical and useful to the development of multifunctional MOF-based catalysts. Herein, a bifunctional Zn-MOF, Zn-ADBA, constructed by photoactive 4,4’-(9,10-anthracenediyl

CuMgAl hydrotalcite as an efficient bifunctional catalyst for the cross-dehydrogenative C–C coupling reactions under mild conditions

CuMgAl layered double hydroxide compounds (CuMgAl-LDHs) have been synthesized, characterized and investigated in the aerobic CDC reactions. The results indicated that NH3·H2O coprecipitated CuMgAl LDH (N-CuMgAl-LDH) was able to effic

Efficient aerobic cross-dehydrogenative coupling of tertiary amines over NiGa layered double oxide

An efficient and convenient heterogeneous catalytic system has been developed for the aerobic cross-dehydrogenative coupling over NiGa layered double oxide (Ni3Ga-LDO) without any additives. The results indicated that the catalytic system could

Cobalt-containing zeolitic imidazole frameworks for C-H activation using visible-light redox photocatalysis

The activation of C-H bonds for carbon-carbon coupling reactions remains a challenge in organic synthesis. Visible light photocatalysis offers a unique opportunity to sustainably perform these reactions in a single-step, without the need for caustic reage

Method for catalyzing oxidation coupling of tetrahydroisoquinoline derivative by hydrotalcite-like material

The invention relates to a method for catalyzing oxidation coupling reaction of a 2-phenyl-1,2,3,4-tetrahydroisoquinoline compound by a hydrotalcite-like material, and belongs to the application fieldof hydrotalcite-like materials. The hydrotalcite-like m