121129-31-5Relevant articles and documents
EFFECT OF AGGREGATION ON STEREOCHEMISTRY AND MECHANISM OF ASYMMETRIC OXIDATION OF THE LITHIUM ENOLATE OF METHYL 3,3-DIMETHYLBUTANOATE IN THE SOLID STATE AND IN SOLUTION
Wei, Yen,Bakthavatchalam, R.,Jin, Xian-Ming,Murphy, Christopher K.,Davis, Franklin A.
, p. 3715 - 3718 (1993)
Oxidation of the title enolate by enantiopure (camphorylsulfonyl)oxaziridines in THF afforded α-hydroxyester with 53-73percent ee, but the product from the solid state reactions was racemic.The results suggest that the enolate exists and reacts as an aggregate in the solid state reactions.
Stereospecific α-methallylation of hydroxyaldehydes by silatropic ene cyclisation
Robertson, Jeremy,Hall, Michael J.,Green, Stuart P.
experimental part, p. 5541 - 5551 (2009/12/09)
We describe the thermal rearrangement of aldehydes bearing an α-(allyl- or crotylsilyl)oxy substituent. The transformations are best described mechanistically as intramolecular silatropic ene reactions based on stereoselectivity, kinetic and computed transition state data. The overall process constitutes a stereospecific (meth)allylation of α-hydroxyaldehydes, under neutral conditions, in which the hydroxyl protecting group is also the (meth)allylating agent.
Rate acceleration of nucleophilic substitution of 2-chloro-4,6- dimethoxypyrimidine by sulfinate catalysis
Bessard, Yves,Crettaz, Roger
, p. 4739 - 4745 (2007/10/03)
The use of sulfinates greatly enhances the rate of substitution in the reaction of 2-chloro-4,6-dimethoxypyrimidine with alkoxy or aryloxy nucleophiles. Pyrimidinyloxy derivatives as intermediates for potent herbicides have been prepared in good yields fr
