121138-45-2

Basic information

• Product Name: N-p-acetoxybenzyl-3-hydroxypiperidine
• CAS NO: 121138-45-2
• Molecular Weight: 249.31
• Mol File: 121138-45-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-p-acetoxybenzyl-3-hydroxypiperidine(CAS DataBase Reference)
• NIST Chemistry Reference: N-p-acetoxybenzyl-3-hydroxypiperidine(121138-45-2)
• EPA Substance Registry System: N-p-acetoxybenzyl-3-hydroxypiperidine(121138-45-2)

Safety Data

• Hazardous Substances Data: 121138-45-2(Hazardous Substances Data)

Upstream product

• 39720-27-9 4-acetoxybenzyl chloride 
• 19260-33-4 p-acetoxybenzyl iodide 
• 64051-79-2 piperidin-3-ol hydrochloride 

Downstream Products

• 121138-46-3 N-p-acetoxybenzyl-3-piperidinyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate 

Relevant articles and documents

Synthesis of expected metabolites of benidipine hydrochloride

(±)-(R*)-2,6-Dimethyl-4-(m-nitrophenyl)-1,4-dihydropyridine-3,5- dicarboxylic acid (R*)-1-benzyl-3-piperidinyl ester, methyl ester hydrochloride (benidipine hydrochloride, KW-3049, 1) a highly potent and long-acting calcium antagonistic 1,4-dihydropyridine derivative, is now under clinical study as an antihypertensive and as an antianginal agent. In order to confirm the structures of the metabolites of KW-3049, 19 compounds were prepared. Among then 11 compounds were found to be metabolites (the compounds 2, 3, 6, 8, 14, 15, 16, 28, 31, 32 and 34) of KW-3049 in rats and/or dogs.