19260-33-4

Basic information

• Product Name: p-acetoxybenzyl iodide
• Synonyms: p-acetoxybenzyl iodide
• CAS NO: 19260-33-4
• Molecular Weight: 276.074
• Mol File: 19260-33-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: p-acetoxybenzyl iodide(CAS DataBase Reference)
• NIST Chemistry Reference: p-acetoxybenzyl iodide(19260-33-4)
• EPA Substance Registry System: p-acetoxybenzyl iodide(19260-33-4)

Safety Data

• Hazardous Substances Data: 19260-33-4(Hazardous Substances Data)

Upstream product

• 39720-27-9 4-acetoxybenzyl chloride 
• 140-39-6 1-acetoxy-4-methylbenzene 
• 6309-46-2 4-acetoxybenzyl alcohol 
• 507-02-8 acetyl iodide 
• 623-05-2 (4-hydroxyphenyl)methanol 

Downstream Products

• 121138-46-3 N-p-acetoxybenzyl-3-piperidinyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate 
• 121138-45-2 N-p-acetoxybenzyl-3-hydroxypiperidine 

Relevant articles and documents

N-Hydroxyphthalimide-Mediated Electrochemical Iodination of Methylarenes and Comparison to Electron-Transfer-Initiated C-H Functionalization

An electrochemical method has been developed for selective benzylic iodination of methylarenes. The reactions feature the first use of N-hydroxyphthalimide as an electrochemical mediator for C-H oxidation to nonoxygenated products. The method provides the basis for direct (in situ) or sequential benzylation of diverse nucleophiles using methylarenes as the alkylating agent. The hydrogen-atom transfer mechanism for C-H iodination allows C-H oxidation to proceed with minimal dependence on the substrate electronic properties and at electrode potentials 0.5-1.2 V lower than that of direct electrochemical C-H oxidation.

Nucleotide and oligonucleotide prodrugs

The present invention discloses compounds of formula (I): which exhibit antiviral properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of anti-HBV