121150-34-3Relevant academic research and scientific papers
INTRAMOLECULAR ENE REACTION ON UNSATURATED THIOKETONES
Motoki, Shinichi,Watanabe, Tsumoru,Saito, Takao
, p. 189 - 192 (1989)
The thermal cyclization of o-(2-substituted allyloxy)thiobenzophenones giving 1,5-oxathiocine derivatives is reported.This is the first example of the new type intramolecular ene reaction of unsaturated thioketones.
MACROCYCLIC FLU ENDONUCLEASE INHIBITORS
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Page/Page column 53; 54; 159; 160, (2020/05/19)
The present invention relates to macrocyclic pyridotriazine derivatives of formula (I) and the pharmaceutically acceptable salts, solvates or or polymorph thereof, and the use of such compounds as a medicament, in particular in the prevention and/or treatment of viral infections caused by viruses belonging to the Orthomyxoviridae famiIy. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, and to the compositions or preparations for use as a medicament, more preferably for the prevention or treatment of viral infections caused by viruses belonging to the Orthomyxoviridae family.
