1211540-92-9

Basic information

• Product Name: 3-broMo-4-chloro-5-fluoropyridine
• Synonyms: 3-broMo-4-chloro-5-fluoropyridine;-broMo-4-chloro-5-fluoropyridine;3-Bromo-4-chloro-6-fluoropyridine;EOS-61444
• CAS NO: 1211540-92-9
• Molecular Formula: C5H2BrClFN
• Molecular Weight: 210.4314832
• EINECS: -0
• Mol File: 1211540-92-9.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 194.6±35.0 °C(Predicted)
• Appearance: /
• Density: 1.829±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 0.49±0.10(Predicted)
• CAS DataBase Reference: 3-broMo-4-chloro-5-fluoropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-broMo-4-chloro-5-fluoropyridine(1211540-92-9)
• EPA Substance Registry System: 3-broMo-4-chloro-5-fluoropyridine(1211540-92-9)

Safety Data

• Hazardous Substances Data: 1211540-92-9(Hazardous Substances Data)

Usage

General Description

3-Bromo-4-chloro-5-fluoropyridine is a chemical compound with the molecular formula C5H2BrClFN. It is a member of the pyridine family, which is a class of aromatic heterocyclic compounds containing a ring of five carbon atoms and one nitrogen atom. This particular compound is a derivative of pyridine, with bromine, chlorine, and fluorine atoms attached to the 3rd, 4th, and 5th carbon atoms, respectively. It is commonly used as an intermediate or building block in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. The presence of halogen atoms in the molecule makes it a versatile starting material for the introduction of various functional groups, allowing for a wide range of chemical transformations and applications.

Upstream product

• 1613192-96-3 3-bromo-4-chloro-5-fluoropyridine hydrochloride 
• 407-20-5 3-bromo-5-fluoropyridine 

Downstream Products

• 1613192-01-0 tert-butyl 1-(3-amino-5-fluoro-4-pyridyl)piperidine-4-carboxylate 
• 1613191-99-3 2-amino-6-fluoro-N-[5-fluoro-4-(4-{[4-(oxetan-3-yl)piperazin-1-yl]carbonyl}piperidin-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide 
• 1613192-96-3 3-bromo-4-chloro-5-fluoropyridine hydrochloride 
• 1613193-36-4 tert-butyl 1-(3-bromo-5-fluoro-4-pyridyl)piperidine-4-carboxylate 

Relevant articles and documents

BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME

Provided is a compound showing excellent antifungal activity against Trichophyton fungus, which is a major causative microorganism of superficial mycosis, and high effectiveness on diseases caused by Trichophyton fungi. A biaryl derivative represented by the formula (I) or a salt thereof: wherein ring A is an optionally substituted phenyl, or an optionally substituted 5- or 6-membered ring heteroaryl (ring A may be further condensed to form an optionally substituted fused ring); Q is CH2, C=O, NH, O, S or the like; X1, X2 and X3 are CR1 or N; Y is CH or N; Z is CR2b or N; R2a and R2b are each a hydrogen atom, a halogen atom, an optionally substituted C1-C6 alkyl group, a C1-C6 haloalkyl group or the like; R2a and R2b may form, together with carbon atoms bonded thereto, an optionally substituted carbocycle, or an optionally substituted heterocycle.

COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE

The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and solid forms of the compounds of this invention. The compounds of this invention have formula I-A or I-B: wherein the variables are as defined herein.

COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE

The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, a