1613193-36-4

Usage

Uses

Used in Pharmaceutical Industry:
Tert-Butyl 1-(3-Bromo-5-Fluoropyridin-4-Yl)Piperidine-4-Carboxylate is used as a building block for the synthesis of bioactive compounds, particularly in the development of new drugs. Its unique structural features and reactivity contribute to the creation of pharmaceutical agents with potential therapeutic applications.
Used in Chemical Industry:
Tert-Butyl 1-(3-Bromo-5-Fluoropyridin-4-Yl)Piperidine-4-Carboxylate is used as a key intermediate in the synthesis of various chemical derivatives. Its presence of a piperidine ring, tert-butyl group, and carboxylate group allows for further chemical modifications and the production of a wide range of compounds with diverse properties and applications.

Upstream product

• 882738-24-1 1-benzyl 4-tert-butyl piperidine-1,4-dicarboxylate 
• 10314-98-4 1-benzyloxycarbonylpiperidine-4-carboxylic acid 
• 892493-65-1 4-piperidinecarboxylic acid tert-butyl ester hydrochloride 
• 1613192-96-3 3-bromo-4-chloro-5-fluoropyridine hydrochloride 
• 138007-24-6 4-tert-butyl piperidine-4-carboxylate 
• 1211540-92-9 3-bromo-4-chloro-5-fluoropyridine 
• 407-20-5 3-bromo-5-fluoropyridine 

Downstream Products

• 1613192-01-0 tert-butyl 1-(3-amino-5-fluoro-4-pyridyl)piperidine-4-carboxylate 
• 1613191-99-3 2-amino-6-fluoro-N-[5-fluoro-4-(4-{[4-(oxetan-3-yl)piperazin-1-yl]carbonyl}piperidin-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide 

Relevant academic research and scientific papers

COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE

The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and solid forms of the compounds of this invention. The compounds of this invention have formula I-A or I-B: wherein the variables are as defined herein.

COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE

The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula (I) or a pharmaceutically acceptable salt, wherein the variables are as devined herein. Moreover, The compounds of this invention have formula (I-A) or a pharmaceutically acceptable salt, wherein the variables are as defined herein.