1212-06-2Relevant academic research and scientific papers
Enantioselective hydrogenation of tetrasubstituted olefins of cyclic β-(acylamino)acrylates
Tang, Wenjun,Wu, Shulin,Zhang, Xumu
, p. 9570 - 9571 (2007/10/03)
Hydrogenation of a series of cyclic β-(acylamino)acrylates with tetrasubstituted olefins has been accomplished successfully with the use of Ru catalysts with chiral biaryl ligands such as C3-TunaPhos, and up to over 99% ee's have been achieved. This methodology provides an efficient catalytic method for the synthesis of both cis and trans chiral cyclic β-amino acid derivatives. Copyright
