1212-30-2

Basic information

• Product Name: 1,3-Bis(2-pyridyl)thiourea
• Synonyms: 1,3-Bis(2-pyridinyl)thiourea;1,3-Bis(2-pyridyl)thiourea
• CAS NO: 1212-30-2
• Molecular Formula: C₁₁H₁₀N₄S
• Molecular Weight: 230.29
• Mol File: 1212-30-2.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 395.1°C at 760 mmHg
• Flash Point: 192.7°C
• Appearance: /
• Density: 1.402g/cm³
• Vapor Pressure: 1.89E-06mmHg at 25°C
• Refractive Index: 1.774
• CAS DataBase Reference: 1,3-Bis(2-pyridyl)thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Bis(2-pyridyl)thiourea(1212-30-2)
• EPA Substance Registry System: 1,3-Bis(2-pyridyl)thiourea(1212-30-2)

Safety Data

• Hazardous Substances Data: 1212-30-2(Hazardous Substances Data)

Usage

General Description

1,3-Bis(2-pyridyl)thiourea is a chemical compound with the molecular formula C12H10N4S. It is a thiourea derivative with two pyridine rings attached to a central thiourea group. 1,3-Bis(2-pyridyl)thiourea is used in various applications, including as a chelating agent for metal ions and as a reagent in organic synthesis. It forms stable complexes with metal ions such as copper and has been studied for its potential use in analytical chemistry and as a catalyst in organic reactions. The compound's structure and properties make it useful in various fields, including coordination chemistry and material science. Additionally, it has potential applications in the pharmaceutical industry due to its ability to form complexes with metal ions.

InChI:InChI=1/C11H10N4S/c16-11(14-9-5-1-3-7-12-9)15-10-6-2-4-8-13-10/h1-8H,(H2,12,13,14,15,16)

Upstream product

• 462-08-8 pyridin-3-ylamine 
• 504-29-0 2-aminopyridine 
• 75-15-0 carbon disulfide 
• 109-09-1 2-chloropyridine 
• 4314-19-6 bis(1H-benzo[d][1,2,3]triazol-1-yl)methanethione 
• 463-71-8 thiophosgene 
• 110-86-1 pyridine 
• 74734-11-5 1H-imidazole-1-carbodithioic acid methyl ester 

Downstream Products

• 102374-06-1 N-(4-butoxy-phenyl)-N',N''-di-[2]pyridyl-guanidine 
• 103208-79-3 N-(4-dodecyloxy-phenyl)-N',N''-di-[2]pyridyl-guanidine 
• 102460-93-5 N-(4-propoxy-phenyl)-N',N''-di-[2]pyridyl-guanidine 
• 102556-95-6 N-(4-pentyloxy-phenyl)-N',N''-di-[2]pyridyl-guanidine 
• 102895-79-4 N-(4-octyloxy-phenyl)-N',N''-di-[2]pyridyl-guanidine 
• 102558-80-5 N-(4-hexyloxy-phenyl)-N',N''-di-[2]pyridyl-guanidine 
• 101570-52-9 N-(4-hydroxy-phenyl)-N',N''-di-[2]pyridyl-guanidine 
• 101735-02-8 4-(N',N''-di-[2]pyridyl-guanidino)-2-hydroxy-benzoic acid 
• 88012-23-1 N-Phenyl-N',N''-dipyrid-2-yl-guanidin 
• 101891-48-9 N-(4-ethoxy-phenyl)-N',N''-di-[2]pyridyl-guanidine 
• 6268-43-5 1,3-di-pyridin-2-yl-urea 
• 52648-45-0 2-pyridylisothiocyanate 

Relevant articles and documents

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Pt(II), Pd(II) and UO2(II) complexes of N,N′-bis(2- pyridyl)thiourea; Structural, thermal and biological studies

Novel complexes of Pt2+, Pd2+ and UO2 2+ with N,N′-bis(2-pyridyl)thiourea (H2BPT) 1 were synthesized. These complexes namely [Pt(HBPT)2] 2, [Pd(HBPT) 2] 3 and [UO2(HBPT)(OAc)(H2O)] 4 , were characterized by elemental analysis and spectral measurements. Suggested structures (square-planar for both 2 and 3 complexes and pentagonal-bipyramidal geometry for 4) were confirmed by applying geometry optimization and conformational analysis. Thermal properties and decomposition kinetics of all compounds are investigated. The interpretation, mathematical analysis and evaluation of kinetic parameters (E, A, ΔH, ΔS and ΔG) of all thermal decomposition stages have been evaluated using Coats-Redfern, Horowitz-Metzger and MKN Methods: The biochemical studies showed that, complex 2 has powerful and complete degradation effect on DNA. The antibacterial screening demonstrated that, complex 2 has the maximum and broad range activities against Gram-positive and Gram-negative bacterial strains.

Synthesis of thioureas in ionic liquid medium

A highly efficient procedure for the synthesis of symmetrical thioureas by means of simple condensation of primary amines and carbon disulfide in 1-butyl-3-methylimidazolium chloride [BMIM][Cl] as a cheap and commercially available ionic liquid is presented. This procedure works for aromatic and aliphatic primary amines and give high to excellent yields of symmetrical thioureas without need for any catalyst or tedious work-up.