1212918-50-7Relevant academic research and scientific papers
Convenient access to L-3,4,5-trioxygenated phenylalanine compounds from L-tyrosine
Zhou, Shengfeng,Zhou, Chen,Lu, Qian,Liu, Xintong,Yuan, Jie,Yu, Xinhong
, (2020)
A convenient and efficient synthesis of L-3,4,5-trioxygenated phenylalanine derivatives from L-tyrosine was developed. Dibromo phenylalanine is converted easily to bis-phenol via copper-catalyzed hydroxylation. The synthetic potential of this methodology has been demonstrated by efficient synthesis of L-3,4,5-trimethoxyphenylalanine methyl ester and one key intermediate of Trabectedin.
