1213455-73-2 Usage
General Description
The chemical compound "(R)-2-(o-ethylphenyl)pyrrolidine" is a pyrrolidine derivative with a chiral center. It is also known as "1-(2-ethylphenyl)-2-pyrrolidine" and has a molecular formula of C13H17N. (R)-2-(o-ethylphenyl)pyrrolidine is commonly used in organic synthesis and pharmaceutical research due to its potential pharmacological properties. It is a white to off-white solid at room temperature and is soluble in a variety of organic solvents. Its specific chemical properties and potential applications make it a valuable compound in the field of chemistry and pharmaceutical science.
Check Digit Verification of cas no
The CAS Registry Mumber 1213455-73-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,3,4,5 and 5 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1213455-73:
(9*1)+(8*2)+(7*1)+(6*3)+(5*4)+(4*5)+(3*5)+(2*7)+(1*3)=122
122 % 10 = 2
So 1213455-73-2 is a valid CAS Registry Number.
1213455-73-2Relevant articles and documents
Zinc-Catalyzed Asymmetric Hydrosilylation of Cyclic Imines: Synthesis of Chiral 2-Aryl-Substituted Pyrrolidines as Pharmaceutical Building Blocks
W?glarz, Izabela,Michalak, Karol,Mlynarski, Jacek
, p. 1317 - 1321 (2021)
The first successful enantioselective hydrosilylation of cyclic imines promoted by a chiral zinc complex is reported. In situ generated zinc-ProPhenol complex with silane afforded pharmaceutically relevant enantioenriched 2-aryl-substituted pyrrolidines in high yields and with excellent enantioselectivities (up to 99% ee). The synthetic utility of presented methodology is demonstrated in an efficient synthesis of the corresponding chiral cyclic amines, being pharmaceutical drug precursors to the Aticaprant and Larotrectinib. (Figure presented.).
