121360-14-3Relevant academic research and scientific papers
Synthetic studies on glycosphingolipids from Protostomia phyla: Total syntheses of glycosphingolipids from the parasite, Echinococcus multilocularis
Yamamura, Takeshi,Hada, Noriyasu,Kaburaki, Asuka,Yamano, Kimiaki,Takeda, Tadahiro
, p. 2749 - 2759 (2007/10/03)
Efficient and systematic syntheses of four neutral glycosphingolipids that have been isolated from the metacestodes of Echinococcus multilocularis have been achieved. A key step is the direct glycosylation of galactosyl donors using thioglycosides with be
Process for producing sialic acid derivatives
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, (2008/06/13)
The present invention provides a process for selective production of a 2-α-O-glycoside compound of sialic acid which is useful as a starting material or intermediate for medicines and biochemical reagents. The process comprises reacting an alkylthiosialic acid derivative represented by the formula [I]: STR1 wherein R represents an acyl group and R1 and R2 each represents a lower alkyl group with a compound having alcoholic hydroxyl group at a low temperature in a polar solvent having no hydroxyl group in the presence of a Lewis acid selected from the group consisting of methyl triflate, trimethylsilyl triflate and dimethyl(methylthio)sulfonium triflate. The present invention further provides novel compounds.
