121372-62-1

Upstream product

• 454-89-7 3-Trifluoromethylbenzaldehyde 
• 74-89-5 methylamine 
• 90390-07-1 N-methyl-1-(3-(trifluoromethyl)phenyl)methanamine 

Downstream Products

• 137944-39-9 N,N'-dimethyl-1,2-bis(3-(trifluoromethyl)phenyl)-1,2-ethanediamine 
• 90390-07-1 N-methyl-1-(3-(trifluoromethyl)phenyl)methanamine 
• 121393-21-3 (4S,5S)-2-((1S,5R)-6,6-Dimethyl-bicyclo[3.1.1]hept-2-en-2-yl)-1,3-dimethyl-4,5-bis-(3-trifluoromethyl-phenyl)-imidazolidine 
• 121393-21-3 (4R,5R)-2-((1S,5R)-6,6-Dimethyl-bicyclo[3.1.1]hept-2-en-2-yl)-1,3-dimethyl-4,5-bis-(3-trifluoromethyl-phenyl)-imidazolidine 
• 121372-68-7 (4S,5S)-2-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-1,3-dimethyl-4,5-bis-(3-trifluoromethyl-phenyl)-imidazolidine 
• 121466-36-2 (4R,5R)-2-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-1,3-dimethyl-4,5-bis-(3-trifluoromethyl-phenyl)-imidazolidine 
• 137944-39-9 (R,R)-N,N'-Dimethyl-1,2-ethylene-1,2-diamine 
• 205873-26-3 (1S,2S)-(+)-N,N'-dimethyl-1,2-bis[3-(trifluoromethyl)phenyl]-1,2-ethanediamine 
• 121372-64-3 Benzoic acid 1-[(4R,5R)-1,3-dimethyl-4,5-bis-(3-trifluoromethyl-phenyl)-imidazolidin-2-yl]-hexyl ester 
• 121372-66-5 Acetic acid 1-{(E)-2-[(4R,5R)-1,3-dimethyl-4,5-bis-(3-trifluoromethyl-phenyl)-imidazolidin-2-yl]-vinyl}-hexyl ester 
• 121372-67-6 (4R,5R)-1,3-Dimethyl-2-(2-phenyl-propyl)-4,5-bis-(3-trifluoromethyl-phenyl)-imidazolidine 
• 121372-63-2 (4R,5R)-2-(2,6-Dimethyl-hept-5-enyl)-1,3-dimethyl-4,5-bis-(3-trifluoromethyl-phenyl)-imidazolidine 
• 121372-65-4 (4R,5R)-1,3-Dimethyl-2-(1-phenyl-ethyl)-4,5-bis-(3-trifluoromethyl-phenyl)-imidazolidine 
• 2640520-10-9 (1S,2R)-N,N'-Dimethyl-1,2-bis-(4-trifluoromethyl-phenyl)-ethane-1,2-diamine 

Relevant academic research and scientific papers

A telescopic one-pot synthesis of β-lactam rings using amines as a convenient source of imines

A facile synthetic approach to substituted β-lactams was designed, using secondary benzylic amines and acid chlorides as starting materials. The reactions proceeded smoothly and all the products were obtained in good yields.

Reactions of N-Halo-N-methylbenzylamines with MeONa-MeOH and t-BuOK-t-BuOH. Effects of β-Carbon Substituent and Base-Solvent System upon the Imine-Forming Transition State

Elimination reactions of YC6H4CH(R)N(X)CH3 in which R = Me and Ph and X = Cl and Br promoted by MeONa-MeOH and t-BuOK-t-BuOH have been studied kinetically.The elimination reactions are regiospecific, producing only the corresponding N-benzylidenemethylami

Benzylamines: Synthesis and evaluation of antimycobacterial properties

The synthesis of benzylamines with various N-alkyl chains and substituents in the aromatic system as well as their evaluation on Mycobacterium tuberculosis H 37 Ra are described. The most active compounds in this test, N-methyl-3-chlorobenzylamine (MIC 10.2 μg/mL), N-methyl-3,5-dichlorobenzylamine (93, MIC 10.2 μg/mL), and N-butyl-3,5-difluorobenzylamine (MIC 6.4 μg/mL), also exhibited a marked inhibitory effect on Mycobacterium marinum and Mycobacterium lufu used for the determination of antileprotic properties. The combination of 93 with aminosalicylic acid, streptomycin, or dapsone exert marked supra-additive effects on M. tuberculosis H 37 Ra.