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ENDOTHELIN (16-21) is a hexapeptide derivative of endothelin, a potent vasoconstrictor and regulator of vascular tone. It is derived from the C-terminal region of mature endothelin-1 and is thought to have similar biological actions as the native peptide. Its significant vasoconstrictor activity and potential role in the regulation of blood pressure and cardiovascular function make it a promising target for therapeutic interventions in various pathological conditions.

121377-67-1

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121377-67-1 Usage

Uses

Used in Pharmaceutical Industry:
ENDOTHELIN (16-21) is used as a research tool for studying the biological actions and mechanisms of endothelin peptides. It helps in understanding the role of endothelin in the regulation of vascular tone and blood pressure, as well as its involvement in pathological conditions such as hypertension, heart failure, and pulmonary arterial hypertension.
Used in Drug Development:
ENDOTHELIN (16-21) is used as a potential therapeutic target for the development of drugs aimed at treating cardiovascular diseases. By modulating the activity of ENDOTHELIN (16-21), it may be possible to develop treatments that alleviate the symptoms and complications associated with these conditions.
Used in Diagnostic Applications:
ENDOTHELIN (16-21) can be used as a biomarker for the diagnosis and monitoring of cardiovascular diseases. Its presence and levels in the body may indicate the severity and progression of certain conditions, aiding in the assessment of patient health and the effectiveness of treatments.
Used in Drug Delivery Systems:
ENDOTHELIN (16-21) can be incorporated into drug delivery systems to enhance the targeting and efficacy of therapeutic agents. By utilizing its specific biological actions, it may be possible to develop targeted drug delivery systems that improve the treatment of cardiovascular diseases and reduce side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 121377-67-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,3,7 and 7 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 121377-67:
(8*1)+(7*2)+(6*1)+(5*3)+(4*7)+(3*7)+(2*6)+(1*7)=111
111 % 10 = 1
So 121377-67-1 is a valid CAS Registry Number.
InChI:InChI=1/C39H57N9O9/c1-7-21(5)32(37(54)46-30(39(56)57)14-23-17-42-27-12-10-9-11-25(23)27)48-38(55)33(22(6)8-2)47-36(53)29(16-31(49)50)45-35(52)28(13-20(3)4)44-34(51)26(40)15-24-18-41-19-43-24/h9-12,17-22,26,28-30,32-33,42H,7-8,13-16,40H2,1-6H3,(H,41,43)(H,44,51)(H,45,52)(H,46,54)(H,47,53)(H,48,55)(H,49,50)(H,56,57)/t21-,22-,26-,28-,29-,30-,32-,33-/m0/s1

121377-67-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name ENDOTHELIN (16-21)

1.2 Other means of identification

Product number -
Other names L-His-L-Leu-L-Asp-L-Ile-L-Ile-L-Trp-OH

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:121377-67-1 SDS

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